(R)-2-methylmalate dehydratase

Class of enzymes (R)-2-methylmalate dehydratase 4.2.1.35 9027-92-3 0047508 The enzyme (R)-2-methylmalate dehydratase (4.2.1.35) catalyzes the chemical reaction (R)-2-methylmalate 2-methylmaleate + H2O This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is {{chem name|(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)}}. Other names in common use include citraconate hydratase, citraconase, citramalate hydro-lyase, (−)-citramalate hydro-lyase, and (R)-2-methylmalate hydro-lyase. This enzyme participates in valine, leucine and isoleucine biosynthesis and c5-branched dibasic acid metabolism. It employs one cofactor, iron. References 1 Subramanian SS, Rao MR 1968 Purification and properties of citraconase J. Biol. Chem. 243 2367–72 4296839 9 10.1016/S0021-9258(18)93483-6 free Biology no Category:EC 4.2.1 Category:Iron enzymes Category:Enzymes of unknown structure