17α-Dihydroequilin

Chemical compound 17β-Dihydroequilin 17α-Dihydroequilenin 17β-Dihydroequilenin (9S,13S,14S,17R)-13-methyl-6,9,11,12,14,15,16,17-octahydrocyclopenta[a]phenanthrene-3,17-diol 17α Dihydroequilin.svg skin-invert-image 225px By mouth Estrogen 651-55-8 G03 CA57 9547222 7826162 48P73794OJ α-Dihydroequilin; 7-Dehydro-17α-estradiol; Estra-1,3,5(10),7-tetraen-3,17α-diol 18 22 2 CC12CCC3C(=CCC4=C3C=CC(=C4)O)C1CCC2O 1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3-5,10,14,16-17,19-20H,2,6-9H2,1H3/t14-,16+,17-,18+/m1/s1 NLLMJANWPUQQTA-SPUZQDLCSA-N 17α-Dihydroequilin, or α-dihydroequilin, also known as 7-dehydro-17α-estradiol, as well as estra-1,3,5(10),7-tetraene-3,17α-diol, is a naturally occurring steroidal estrogen found in horses which is closely related to equilin, equilenin, and 17α-estradiol. Fritz MA, Speroff L Clinical Gynecologic Endocrinology and Infertility https://books.google.com/books?id=KZLubBxJEwEC&pg=PA751 28 March 2012 Lippincott Williams & Wilkins 978-1-4511-4847-3 751–IARC Working Group on the Evaluation of Carcinogenic Risks to Humans World Health Organization International Agency for Research on Cancer Combined Estrogen-progestogen Contraceptives and Combined Estrogen-progestogen Menopausal Therapy https://books.google.com/books?id=aGDU5xibtNgC&pg=PA378 2007 World Health Organization 978-92-832-1291-1 378– The compound, as the 3-sulfate ester sodium salt, is present in conjugated estrogens (Premarin), a pharmaceutical extract of the urine of pregnant mares, and is the third highest quantity constituent in the formulation (13.8%). The compound has been studied clinically. Wilcox JG, Stanczyk FZ, Morris RS, Gentzschein E, Lobo RA Biologic effects of 17 alpha-dihydroequilin sulfate Fertility and Sterility 66 5 748–52 November 1996 8893678 10.1016/S0015-0282(16)58629-4 free See also List of estrogens § Equine estrogens References Category:Secondary alcohols Category:Estranes Category:Estrogens