1-Octacosanol

28-carbon primary fatty alcohol July 2020 changed changed 477208352 1-Octacosanol-folded.svg 200px Octacosan-1-ol n-Octacosanol; Octacosyl alcohol; Octanosol; Montanyl alcohol; Cluytyl alcohol C08387 correct kegg 1/C28H58O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29/h29H,2-28H2,1H3 CNNRPFQICPFDPO-UHFFFAOYAC correct chemspider 1S/C28H58O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29/h29H,2-28H2,1H3 correct chemspider CNNRPFQICPFDPO-UHFFFAOYSA-N 557-61-9 changed ?? 68406 OCCCCCCCCCCCCCCCCCCCCCCCCCCCC 61689 correct chemspider 81I2215OVK correct FDA 28243 correct EBI 1-octacosanol 28 58 1 83 1-Octacosanol (also known as n-octacosanol, octacosyl alcohol, cluytyl alcohol, montanyl alcohol) is a straight-chain aliphatic 28-carbon primary fatty alcohol that is common in the epicuticular waxes of plants, including the leaves of many species of Eucalyptus, of most forage and cereal grasses, of Acacia, Trifolium, Pisum and many other legume genera among many others, sometimes as the major wax constituent.EA Baker (1982) Chemistry and morphology of plant epicuticular waxes. pp. 139–165. In "The Plant Cuticle". edited by DF Cutler, KL Alvin and CE Price. Academic Press, London. 0-12-199920-3 Octacosanol also occurs in wheat germ.Octacosanol Natural Products (Professional) drugs.com https://www.drugs.com/npp/octacosanol.html isolated from wheat germ oil or other plants 9 July 2009 https://web.archive.org/web/20090603230755/http://www.drugs.com/npp/octacosanol.html 3 June 2009 live Chemistry Octacosanol is insoluble in water but freely soluble in low molecular-weight alkanes and in chloroform. Biological effects Octacosanol is the main component in the mixture policosanol. 10.1016/S0899-9007(02)00869-9 Octacosanol in human health 2003 Taylor Johanna C Rapport Lisa Lockwood G.Brian Nutrition 19 2 192–5 12591561 Octacosanol has been subject to preliminary study for its potential benefit for patients with Parkinson's disease. 6395790 1984 Snider SR Octacosanol in parkinsonism 16 6 723 10.1002/ana.410160615 Annals of Neurology 43313071 20581854 2010 Wang T Liu YY Wang X Yang N Zhu HB Zuo PP Protective effects of octacosanol on 6-hydroxydopamine-induced Parkinsonism in rats via regulation of ProNGF and NGF signaling 31 7 765–74 10.1038/aps.2010.69 Acta Pharmacologica Sinica 4007727 Studies have also found that octacosanol may inhibit the production of cholesterol. In mice, octacosanol reduces stress and restores stress-affected sleep back to normal. Kaushik MK Aritake K Takeuchi A Yanagisawa M Urade Y Octacosanol restores stress-affected sleep in mice by alleviating stress Scientific Reports 21 August 2017 7 1 8892 10.1038/s41598-017-08874-2 free 28827687 5566941 2017NatSR...7.8892K References Category:Fatty alcohols Category:Primary alcohols Category:Alkanols