2,6-Dimethylpiperidine

changed changed 477212143 2,6-Dimethylpiperidine Dimethylpiperidine.png Structure of 2,6-dimethylpiperidine 2,6-Dimethylpiperidine 2,6-Lupetidine; nanofin; nanophyn CC1CCCC(C)N1 correct chemspider 62076 1/C7H15N/c1-6-4-3-5-7(2)8-6/h6-8H,3-5H2,1-2H3 SDGKUVSVPIIUCF-UHFFFAOYAU N1C(C)CCCC1C correct chemspider 1S/C7H15N/c1-6-4-3-5-7(2)8-6/h6-8H,3-5H2,1-2H3 correct chemspider SDGKUVSVPIIUCF-UHFFFAOYSA-N changed ?? 504-03-0 OK5775000 68843 207-981-6 329I5805BP 2104431 7 15 1 Colorless liquid 0.84 g/mL Low other solvents Most organic solvents 113.2 ca. 10 1.4394 Flammable 11 02 05 07 Danger 225 314 315 319 335 210 233 240 241 242 243 260 261 264 271 280 301+330+331 302+352 303+361+353 304+340 305+351+338 310 312 321 332+313 337+313 362 363 370+378 403+233 403+235 405 501 Piperidine 2,6-Dimethylpiperidines are chemical compounds with the formula C5H8(CH3)2NH. Three stereoisomers exist: the achiral (R,S)-isomer and the chiral (R,R)/(S,S) enantiomeric pair. Dimethylpiperidines are derivatives of the heterocycle piperidine, wherein two hydrogen atoms are replaced by methyl groups. The 2,6-dimethylpiperidines are prepared by reduction of 2,6-dimethylpyridine (2,6-lutidine). The achiral isomer is the predominant isomer produced in this reaction. The 2,6-dimethylpiperidines are of interest for their conformational properties. The (R,S)-isomer exists largely in the chair conformation with equatorial methyl groups. The (R,R)/(S,S)-isomers are attractive chiral secondary amine building blocks.Einhorn, J.; Einhorn, C.; Ratajczak, F.; Durif, A.; Averbuch, M.-T. and Pierre, J.-L., "Synthesis and resolution of a chiral analog of 2,2,6,6-tetramethylpiperidine and of its corresponding nitroxide", Tetrahedron Letters, 1998, volume 39, pages 2565-2568 References See also Compound Summary 2,6-Dimethylpiperidine on National Library of Medicine National Center Category:Piperidines