2-Hydroxy-1,4-benzoxazin-3-one monooxygenase

Class of enzymes 2-Hydroxy-1,4-benzoxazin-3-one monooxygenase 1.14.14.110 2-Hydroxy-1,4-benzoxazin-3-one monooxygenase (1.14.14.110, BX5 (gene), CYP71C3 (gene)) is an enzyme with systematic name 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one,NAD(P)H:oxygen oxidoreductase (N-hydroxylating). Bailey BA, Larson RL Maize microsomal benzoxazinone N-monooxygenase Plant Physiology 95 3 792–6 March 1991 16668055 1077607 10.1104/pp.95.3.792 Glawischnig E, Grün S, Frey M, Gierl A Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses Phytochemistry 50 6 925–30 March 1999 10385992 10.1016/s0031-9422(98)00318-5 1999PChem..50..925G This enzyme catalyses the following chemical reaction 55% Q27132690 HBOA O2 H2O Q27132689 2,4-dihydroxy-1,4-benzoxazinone thumb|DIMBOA The enzyme is a cytochrome P450 protein containing heme, isolated from maize and other grasses. It requires a partner cytochrome P450 reductase for functional expression. This uses nicotinamide adenine dinucleotide phosphate.1.14.14.110 It is involved in the biosynthesis of protective and allelopathic compounds such as DIMBOA in some plants. Frey M, Chomet P, Glawischnig E, Stettner C, Grün S, Winklmair A, Eisenreich W, Bacher A, Meeley RB, Briggs SP, Simcox K, Gierl A Analysis of a chemical plant defense mechanism in grasses Science 277 5326 696–9 August 1997 9235894 10.1126/science.277.5326.696 References External links 2-hydroxy-1,4-benzoxazin-3-one+monooxygenase Biology no Category:EC 1.14.14