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411 REFERENCE · Wikipedia

2-Carboxy-D-arabitinol 1-phosphate

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{{DISPLAYTITLE:2-Carboxy-D-arabitinol 1-phosphate}} 2-Carboxy-D-arabitinol 1-phosphate 2-Carboxy-D-arabitinol 1-phosphate.svg 200px 2-C-[(Phosphonooxy)methyl]-D-ribonic acid (2R,3R,4R)-2,3,4,5-Tetrahydroxy-2-[(phosphonooxy)methyl]pentanoic acid CA1P 106777-19-9 changed EPA 17541 114616 C04234 129417 ZFW7MEG9NT OC[C@@H](O)[C@@H](O)[C@](O)(COP(O)(O)=O)C(O)=O 1S/C6H13O10P/c7-1-3(8)4(9)6(12,5(10)11)2-16-17(13,14)15/h3-4,7-9,12H,1-2H2,(H,10,11)(H2,13,14,15)/t3-,4-,6-/m1/s1 UJTMIRNFEXKGMS-ZMIZWQJLSA-N 6 13 10 1 2-Carboxy-D-arabitinol 1-phosphate (CA1P) is a molecule produced in plants that inhibits RuBisCO, a key enzyme in the Calvin cycle and carbon fixation. In dark conditions, this molecule binds to RuBisCO, preventing it from participating in chemical reactions. As the amount of light present increases, CA1P levels decrease, freeing RuBisCO's reactive ends, allowing more of the molecules to participate in chemical reactions. It is removed from Rubisco's active sites through the action of Rubisco activase (Rca)Bhat Javaid Y. Miličić Goran Thieulin-Pardo Gabriel Bracher Andreas Maxwell Andrew Ciniawsky Susanne Mueller-Cajar Oliver Engen John R. Hartl F. Ulrich Wendler Petra Hayer-Hartl Manajit 2017-09-07 Mechanism of Enzyme Repair by the AAA+ Chaperone Rubisco Activase https://www.cell.com/molecular-cell/abstract/S1097-2765(17)30498-7 Molecular Cell English 67 5 744–756.e6 10.1016/j.molcel.2017.07.004 1097-2765 28803776 and is broken down by the enzyme 2-carboxy-D-arabinitol-1-phosphatase into 2-carboxy-D-arabinitol.Servaites JC Inhibition of ribulose 1,5-bisphosphate carboxylase/oxygenase by 2-carboxyarabinitol-1-phosphate. Plant Physiol 1990 92 4 867–70 16667398 10.1104/pp.92.4.867 1062388 References Category:Organophosphates Category:Enzyme inhibitors