(S)-usnate reductase

Class of enzymes (S)-usnate reductase 1.1.1.199 77237-99-1 0046998 In enzymology, (S)-usnate reductase (1.1.1.199) is an enzyme that catalyzes the chemical reaction 60% Q27121480 (S)-usnic acid precursor + NAD+ reversible H+ H+ Q27105250 (S)-usnic acid + NADH The enzyme converts the precursor (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one into (S)-usnic acid using oxidised nicotinamide adenine dinucleotide (NAD+) as cofactor and forming an ether bond.1.1.1.199Barbini N, Gorini G, Ferrucci L, Biggeri A 2005 [Analysis of arterial hypertension and work in the epidemiologic study "Aging, Health and Work"] Epidemiol. Prev. 29 160–165 16454408 3–4 This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming). This enzyme is also called L-usnic acid dehydrogenase. References Biology no Category:EC 1.1.1 Category:NADH-dependent enzymes Category:Enzymes of unknown structure