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16-alpha-hydroxysteroid dehydrogenase
Reference material by Wikipedia contributors. This retains its source identity and is not 411 news reporting.
Class of enzymes
16-alpha-hydroxysteroid dehydrogenase 1.1.1.147 37250-74-1 0047005
In enzymology, a 16alpha-hydroxysteroid dehydrogenase (1.1.1.147) is an enzyme that catalyzes the chemical reaction
a 16alpha-hydroxysteroid + NAD(P)+ a 16-oxosteroid + NAD(P)H + H+
The 3 substrates of this enzyme are 16alpha-hydroxysteroid, NAD+, and NADP+, whereas its 4 products are 16-oxosteroid, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 16alpha-hydroxysteroid:NAD(P)+ 16-oxidoreductase. This enzyme is also called 16alpha-hydroxy steroid dehydrogenase.
References
1
Meigs RA, Ryan KJ 1966 16-alpha-hydroxysteroid dehydrogenase of rat kidney. Purification, assay, and properties J. Biol. Chem. 241 4011–5 4380686 17 10.1016/S0021-9258(18)99804-2 free
Biology no
Category:EC 1.1.1
Category:NADPH-dependent enzymes
Category:NADH-dependent enzymes
Category:Enzymes of unknown structure