2-furoyl-CoA dehydrogenase

In enzymology, a 2-furoyl-CoA dehydrogenase (EC 1.3.99.8) is an enzyme that catalyzes the chemical reaction 2-furoyl-CoA + H2O + acceptor ⇌ {\displaystyle \rightleftharpoons } S-(5-hydroxy-2-furoyl)-CoA + reduced acceptor The 3 substrates of this enzyme are 2-furoyl-CoA, H2O, and acceptor, whereas its two products are S-(5-hydroxy-2-furoyl)-CoA and reduced acceptor. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is 2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating). Commonly used names include furoyl-CoA hydroxylase, 2-furoyl coenzyme A hydroxylase, 2-furoyl coenzyme A dehydrogenase, and 2-furoyl-CoA:(acceptor) 5-oxidoreductase (hydroxylating). It employs one cofactor, copper. == References == Kitcher JP, Trudgill PW, Rees JS (1972). "Purification and properties of 2-furoyl-coenzyme A hydroxylase from Pseudomonas putida F2". Biochem. J. 130 (1): 121–32. doi:10.1042/bj1300121. PMC 1174307. PMID 4655411.