2,6-dioxo-6-phenylhexa-3-enoate hydrolase

Class of enzymes 2,6-dioxo-6-phenylhexa-3-enoate hydrolase 3.7.1.8 102925-38-2 0018774 In enzymology, a 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (3.7.1.8) is an enzyme that catalyzes the chemical reaction 2,6-dioxo-6-phenylhexa-3-enoate + H2O benzoate + 2-oxopent-4-enoate Thus, the two substrates of this enzyme are 2,6-dioxo-6-phenylhexa-3-enoate and H2O, whereas its two products are benzoate and 2-oxopent-4-enoate. This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is 2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase. This enzyme is also called HOHPDA hydrolase. This enzyme participates in biphenyl degradation and fluorene degradation. Structural studies As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1C4X, 1J1I, and 2OG1. References 1 Omori T, Sugimura K, Ishigooka H, Minoda Y 1986 Purification and some properties of a 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolyzing enzyme from Pseudomonas cruciviae S93 B1 involved in the degradation of biphenyl Agric. Biol. Chem. 50 4 931–937 10.1271/bbb1961.50.931 free Biology no Category:EC 3.7.1 Category:Enzymes of known structure