2,4-Dichlorobenzoyl-CoA reductase

Class of enzymes 2,4-dichlorobenzoyl-CoA reductase 1.3.1.63 0018516 In enzymology, a 2,4-dichlorobenzoyl-CoA reductase (1.3.1.63) is an enzyme that catalyzes the chemical reaction 4-chlorobenzoyl-CoA + NADP+ + HCl 2,4-dichlorobenzoyl-CoA + NADPH + H+ The 3 substrates of this enzyme are 4-chlorobenzoyl-CoA, NADP+, and HCl, whereas its 3 products are 2,4-dichlorobenzoyl-CoA (the thioester of 2,4-dichlorobenzoic acid), NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating). This enzyme participates in degradation of 2,4-dichlorobenzoate. References Romanov V, Hausinger RP 1996 NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strainNTB-1 via 2,4-dichlorobenzoyl coenzyme A J. Bacteriol. 178 2656–61 8626335 9 10.1128/jb.178.9.2656-2661.1996 177992 Biology no Category:EC 1.3.1 Category:NADPH-dependent enzymes Category:Enzymes of unknown structure