(R,R)-butanediol dehydrogenase

Class of enzymes (R,R)-butanediol dehydrogenase 1.1.1.4 37250-09-2 0000721 1geg assembly.png Meso-2,3-butanediol dehydrogenase from Klebsiella pneumoniae. PDB 1geg In enzymology, (R,R)-butanediol dehydrogenase (1.1.1.4) is an enzyme that catalyzes the chemical reaction 50% Q27102161 (R,R)-butane-2,3-diol + NAD+ reversible H+ H+ Q27098190 R-acetoin + NADH The two substrates of this enzyme are (R,R)-butane-2,3-diol and NAD+; its products are (R)-acetoin, nicotinamide adenine dinucleotide (NADH), and a proton.1.1.1.4 Strecker HJ, Harary I Bacterial butylene glycol dehydrogenase and diacetyl reductase The Journal of Biological Chemistry 211 1 263–70 November 1954 10.1016/S0021-9258(18)71216-7 13211662 free Taylor MB, Juni E Stereoisomeric specificities of 2,3-butanediol dehydrogenases Biochimica et Biophysica Acta 39 3 448–57 April 1960 13837186 10.1016/0006-3002(60)90197-9 This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R,R)-butane-2,3-diol:NAD+ oxidoreductase. Other names in common use include butyleneglycol dehydrogenase, D-butanediol dehydrogenase, D-(−)-butanediol dehydrogenase, butylene glycol dehydrogenase, diacetyl (acetoin) reductase, D-aminopropanol dehydrogenase, D-aminopropanol dehydrogenase, 1-amino-2-propanol dehydrogenase, 2,3-butanediol dehydrogenase, D-1-amino-2-propanol dehydrogenase, (R)-diacetyl reductase, (R)-2,3-butanediol dehydrogenase, D-1-amino-2-propanol:NAD+ oxidoreductase, 1-amino-2-propanol oxidoreductase, and aminopropanol oxidoreductase. This enzyme participates in butanoic acid metabolism. References 1 Biology no Category:EC 1.1.1 Category:NADH-dependent enzymes