2,8-Dihydroxyhexahydrochrysene

Chemical compound 2,8-Dihydroxyhexahydrochrysene.svg skin-invert-image correct CAS 71563-78-5 None 12519776 23351465 18 18 2 OC1C=CC2=C(C=1)CCC3C2CCC4C3=CC=C(O)C=4 1S/C18H18O2/c19-13-3-7-15-11(9-13)1-5-17-16-8-4-14(20)10-12(16)2-6-18(15)17/h3-4,7-10,17-20H,1-2,5-6H2 WKSBLYZBEPGLTB-UHFFFAOYSA-N 2,8-Dihydroxyhexahydrochrysene (2,8-DHHHC) is a synthetic, nonsteroidal weak estrogen with approximately 1/2,000th the estrogenic potency of the structurally-related estrogen diethylstilbestrol. Maximov PY, McDaniel RE, Jordan VC Tamoxifen: Pioneering Medicine in Breast Cancer https://books.google.com/books?id=p-W5BAAAQBAJ&pg=PA4 23 July 2013 Springer Science & Business Media 978-3-0348-0664-0 4– Virgil Craig Jordan vanc Estrogen/antiestrogen Action and Breast Cancer Therapy https://books.google.com/books?id=7WmLZfGXST0C&pg=PA22 1986 Univ of Wisconsin Press 978-0-299-10480-1 22– Wilds AL, Sutton RE Cyclic Analogs of Hexestrol in the Chrysene Series The Journal of Organic Chemistry 16 9 1951 1371–1379 0022-3263 10.1021/jo50003a006 It is said to be intermediate in structure between estradiol and hexestrol, but conversely to both of them, it is drastically less potent in comparison. See also Tetrahydrochrysene Chrysene Triphenylethylene Estrobin Stilbestrol Methallenestril Ethamoxytriphetol References Category:Synthetic estrogens Category:Hydroxyarenes