2,6-Xylidine

2,6-Xylidin.svg 150px 2,6-Dimethylaniline 2,6-Dimethylbenzene-1-amine 2,6-Dimethylbenzenamine 2,6-Dimethylphenylamine correct chemspider 6630 correct kegg C11004 1/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 UFFBMTHBGFGIHF-UHFFFAOYAI correct chemspider 1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3 correct chemspider UFFBMTHBGFGIHF-UHFFFAOYSA-N correct CAS 87-62-7 correct FDA 4FT62OX08D 6896 correct EBI 28738 Nc1c(cccc1C)C 8 11 1 Colorless liquid 0.9842 g/mL 11.45 215 1.5601 2,6-Xylidine is an organic compound with the formula C6H3(CH3)2NH2. It is one of several isomeric xylidines. It is a colorless viscous liquid. Commercially significant derivatives are the anesthetics lidocaine, bupivacaine, mepivacaine, and etidocaine.M. Meyer Xylidines Ullmann's Encyclopedia of Industrial Chemistry Wiley-VCH Weinheim 2012 10.1002/14356007.a28_455 9783527303854 Production, occurrence, reactions Many xylidines are prepared by nitration of a xylene followed by hydrogenation of the nitroaromatic, but this approach is not efficient for this isomer. Instead, it is prepared from by treatment of the related xylenol with ammonia in the presence of oxide catalysts. 2,6-Xylidine is also a major metabolite of the drug xylazine in both horses,Spyridaki M.-H. Lyris E. Georgoulakis I. Kouretas D. Konstantinidou M. Georgakopoulos C. G. 2004-04-01 Determination of xylazine and its metabolites by GC-MS in equine urine for doping analysis Journal of Pharmaceutical and Biomedical Analysis 35 1 107–116 10.1016/j.jpba.2003.12.007 0731-7085 15030885 and humans.https://www.deadiversion.usdoj.gov/drug_chem_info/Xylazine.pdf Xylazine February 2021 Drug Enforcement Administration Diversion Control Division Drug & Chemical Evaluation Section DEA PRB # 2021-15 2022-11-15 2,6-Xylidine is the precursor to the NHC ligand called Xyl. 10.1021/ed300243s Synthesis of Well-Defined CopperN-Heterocyclic Carbene Complexes and Their Use as Catalysts for a "Click Reaction": A Multistep Experiment That Emphasizes the Role of Catalysis in Green Chemistry Journal of Chemical Education 89 12 1575 2012 Ison Elon A. Ison Ana 2012JChEd..89.1575I Uses 2,6-Xylidine is a precursor to the fungicide metalaxyl10.1023/A:1019164928084 1997 Blaser Hans-Ulrich Spindler Felix Enantioselective catalysis for agrochemicals. The case histories of (S)–metolachlor, (R)–metalaxyl and clozylacon Topics in Catalysis 4 3/4 275–282 and the herbicide metazachlor de.Unger Thomas A. Pesticide Synthesis Handbook William Andrew 1996-12-31 0-8155-1853-6 35 thumb|center|Synthesis of metazachlor References Category:IARC Group 2B carcinogens Category:Anilines