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2-Methyl-DiPT
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2-Methyl-DiPT chemical structure.svg skin-invert-image 200px Unknown Unknown None Unknown 2-Me-DiPT; 2-Methyl-N,N-diisopropyltryptamine N-[2-(2-methyl-1H-indol-3-yl)ethyl]-N-propan-2-ylpropan-2-amine 17 26 2 CC(N(C(C)C)CCC(C1=CC=CC=C1N2)=C2C)C 1S/C17H26N2/c1-12(2)19(13(3)4)11-10-15-14(5)18-17-9-7-6-8-16(15)17/h6-9,12-13,18H,10-11H2,1-5H3 VRRKLUAGPLTKAR-UHFFFAOYSA-N
2-Methyl-DiPT, or 2-Me-DiPT, also known as 2-methyl-N,N-diisopropyltryptamine, is a chemical compound of the tryptamine family related to the psychedelic drug diisopropyltryptamine (DiPT). "There is an interesting idea tucked away here in what seems to be an uninteresting compound. The sound distortion, mentioned in both of these reports, brings to mind DIPT where it is the major indicator of intoxication. With some people, it is the only change observed. With DIPT, there are two isopropyl groups on the basic nitrogen atom; here there are two ethyl groups. One might speculate that there might well be some optimum group geometry that would make the auditory to visual distortion ratio as high as possible. There were no suggestions that there were any auditory changes with DET so perhaps the added mass of that methyl group at the 2-position brings the molecular weight into some "auditory window." A compelling compound would be, of course, N,N-diisopropyl-2-methyltryptamine (2-Me-DIPT), but I don't believe that it has ever even been synthesized as of the present moment. It would certainly be a simple compound to make." It is the 2-methyl derivative of DiPT.
The drug was mentioned by Alexander Shulgin in his book TiHKAL (Tryptamines I Have Known and Loved) as a potentially interesting analogue of DiPT that might likewise produce selective auditory hallucinogenic effects. This was based on findings that other 2-methylated tryptamines like 2-methyl-DMT and 2-methyl-DET have also uniquely been found to produce DiPT-like auditory effects. However, 2-methyl-DiPT is not known to have been synthesized nor tested.
A notable derivative of 2-methyl-DiPT is 5-MeO-2-Me-DiPT. Brandt SD, Tearavarich R, Dempster N, Cozzi NV, Daley PF Synthesis and characterization of 5-methoxy-2-methyl-N,N-dialkylated tryptamines Drug Test Anal 4 1 24–32 January 2012 22287290 10.1002/dta.398 Caspar AT, Gaab JB, Michely JA, Brandt SD, Meyer MR, Maurer HH Metabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT and their detectability in urine studied by GC-MS, LC-MSn , and LC-HR-MS/MS Drug Test Anal 10 1 184–195 January 2018 28342193 10.1002/dta.2197 https://researchonline.ljmu.ac.uk/id/eprint/6076/1/DTA-17-0077.R1_accepted_uncorrected.pdf In addition, a notable analogue of 2-methyl-DiPT is 2-methyl-iPALT. Asymmetric allyl tryptamines 20240277665A1 US 4 March 2024 https://patents.google.com/patent/US20240277665A1 Daley PF, Cozzi NV, Callaway WB Alexander Shulgin Research Institute Inc.
2-Methyl-DiPT was first described by Shulgin in TiHKAL in 1997.
See also
Substituted tryptamine
References
Category:2-Alkyltryptamines
Category:N,N-Dialkyltryptamines
Category:Diisopropylamino compounds