1,2,4-Trichlorobenzene

changed changed 477202699 1,2,4-trichlorobenzene.svg skin-invert 1,2,4-trichlorobenzene-3D-vdW.png bg-transparent 1,2,4-Trichlorobenzene correct chemspider 13862559 correct CAS 120-82-1 correct FDA 05IQ959M1N 13 Clc1ccc(Cl)c(Cl)c1 1/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H< changed EBI 28222 correct kegg 6 3 3 Colorless liquid aromatic 1.46 g cm−3 16.9 213.5 Jaw Ching-Guang Chen I-Ming Yen Jui-Hung Wang Yei-Shung December 1999 Partial solubility parameters of chlorobenzene and chlorophenol compounds at equilibrium distribution in two immiscible phases Chemosphere 39 15 2607–2620 10.1016/s0045-6535(99)00173-3 0045-6535 0.003% (20 °C) 1 mmHg (20 °C) 110 2.5%–6.6% (150°C) none N.D.0627 C 5 ppm (40 mg/m3) 1,2,3-Trichlorobenzene1,3,5-Trichlorobenzene 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. It is a derivative of benzene with three chloride substituents. It is a colorless liquid used as a solvent for a variety of compounds and materials. Production and uses Depending on the conditions and additives (e.g., sulfur), it can be the main product from the chlorination of benzene. It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. It is also the main product from the dehydrochlorination of hexachlorocyclohexane. Beck, U. Löser, E. Chlorinated Benzenes and other Nucleus-Chlorinated Aromatic Hydrocarbons 10.1002/14356007.o06_o03 It is useful as a high-temperature solvent, e.g. for gel permeation chromatography of polyolefins such as polyethylene or polypropylene. Aside from its use as a solvent, this compound is a useful precursor to dye and pesticides. Safety The LD50 (oral, rats) is 756 mg/kg. Animal studies have shown that 1,2,4-trichlorobenzene affects the liver and kidney, and is possibly a teratogen.CDC - NIOSH Pocket Guide to Chemical Hazards There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday. See also Chlorobenzenes—different numbers of chlorine substituents and isomeric forms References Category:Chlorobenzenes Category:Halogenated solvents Category:Aromatic solvents