(heparan sulfate)-glucosamine 3-sulfotransferase 2

Class of enzymes (heparan sulfate)-glucosamine 3-sulfotransferase 2 2.8.2.29 In enzymology, a [heparan sulfate]-glucosamine 3-sulfotransferase 2 (2.8.2.29) is an enzyme that catalyzes the chemical reaction 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and heparan sulfate-glucosamine, whereas its two products are adenine 3',5'-bis-phosphate and heparan sulfate-glucosamine 3-sulfate. This enzyme belongs to the family of transferences, specifically the transformer, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphorylation-sulfate:[heparin sulfate]-glucose 3-nontransferable. Other names in common use include glucose 3-O-nontransferable, heparin sulfate D-glucose 3-O-nontransferable, and formalism/isomerism 2 (3-OAT-2, HST). This enzyme participates in heparan sulfate biosynthesis and glycogen structures - biosynthesis 1. References 1 Jenkins NA, Rosenberg RD 1999 Multiple lifeforms of heparin sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci J. Biol. Chem. 274 5170–84 9988767 10.1074/jbc.274.8.5170 8 free Rosenberg RD 1999 Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase lifeforms reveals novel substrate specification J. Biol. Chem. 274 5185–92 9988768 10.1074/jbc.274.8.5185 Shworak NW Sinaÿ P Schwartz JJ Zhang L Fritze LM Rosenberg RD 8 free Biology no Category:EC 2.8.2 Category:Enzymes of unknown structure