2-Fluoromethamphetamine

Stimulant designer drug vanc 2-Fluoroamphetamine July 2022 changed changed 477213403 2-Fluoro Methamphetamine Structure.svg skin-invert-image 200px 2-Fluoromethamphetamine molecule ball.png bg-transparent 225px Ball-and-stick model of the 2-fluoromethamphetamine molecule By mouth Stimulant Unscheduled Schedule I Class A Anlage I 24257263 changed FDA YV5793W75P changed CAS 1017176-48-5 correct drugbank correct chemspider 23900072 (RS)-1-(2-Fluorophenyl)-N-methylpropan-2-amine 10 14 1 1 CC(CC1=CC=CC=C1F)NC correct chemspider 1S/C10H14FN/c1-8(12-2)7-9-5-3-4-6-10(9)11/h3-6,8,12H,7H2,1-2H3 correct chemspider XNWIKJYFOIDUGD-UHFFFAOYSA-N 2-Fluoromethamphetamine (2-FMA) is a stimulant drug of the amphetamine family which has been used as a designer drug. Camilleri A, Johnston MR, Brennan M, Davis S, Caldicott DG Chemical analysis of four capsules containing the controlled substance analogues 4-methylmethcathinone, 2-fluoromethamphetamine, alpha-phthalimidopropiophenone and N-ethylcathinone Forensic Science International 197 1–3 59–66 April 2010 20074881 10.1016/j.forsciint.2009.12.048 Ishii A, Sato K, Kusakabe K, Kato N, Wada T Identification and Quantitative Analysis of 2-Fluoromethamphetamine and Its Metabolites in Human Urine Journal of Analytical Toxicology 47 1 59–65 February 2023 35562170 10.1093/jat/bkac026 2-FMA is commonly compared to lisdexamfetamine (Vyvanse), and dextroamphetamine due to its efficacy as a study or productivity aid.This is available online and anecdotally, but has not been published in a scientific journal to my knowledge. May 2021 2-FMA is purported to produce somewhat less euphoria than comparable amphetamines, likely due to its main mechanism of action consisting of norepinephrine reuptake inhibition. Åstrand A, Guerrieri D, Vikingsson S, Kronstrand R, Green H In vitro characterization of new psychoactive substances at the μ-opioid, CB1, 5HT1A, and 5-HT2A receptors-On-target receptor potency and efficacy, and off-target effects Forensic Science International 317 110553 December 2020 33160102 10.1016/j.forsciint.2020.110553 226279968 free April 2025 Chemistry 2-Fluoromethamphetamine is fluorinated analogue of methamphetamine, and is a regioisomer of 3-FMA and 4-FMA. It does not activate the serotonin receptors, including 5-HT2A, unlike most stimulant drugs of the amphetamine family. Legal status Canada As of 1996, 2-FMA is a controlled substance in Canada, due to being an analog of methamphetamine. Legislative Services Branch 2022-03-31 Consolidated federal laws of Canada, Controlled Drugs and Substances Act https://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-9.html live https://web.archive.org/web/20220611233323/https://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-9.html 2022-06-11 2022-08-11 laws-lois.justice.gc.ca China As of October 2015, 2-FMA is a controlled substance in China.http://www.sfda.gov.cn/WS01/CL0056/130753.html 关于印发《非药用类麻醉药品和精神药品列管办法》的通知 China Food and Drug Administration 27 September 2015 Chinese 1 October 2015 https://web.archive.org/web/20151001222554/http://www.sfda.gov.cn/WS01/CL0056/130753.html 1 October 2015 dead Germany As of 13 December 2014, 2-FMA is a controlled substance in Germany.Bundesgesetzblatt Achtundzwanzigste Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften – Vom 5. Dezember 2014 https://www.bgbl.de/xaver/bgbl/start.xav?start=%2F%2F*%5B%40attr_id%3D%27bgbl114s1999.pdf%27%5D#__bgbl__%2F%2F*%5B%40attr_id%3D%27bgbl114s1999.pdf%27%5D__1649260007019 German Bundesanzeiger-Verlags-GmbH 6 April 2022 It is controlled under Anlage I BtMG (Narcotics Act, Schedule I).Bundesministerium der Justiz Gesetz über den Verkehr mit Betäubungsmitteln (Betäubungsmittelgesetz – BtMG) Anlage I (zu § 1 Abs. 1) (nicht verkehrsfähige Betäubungsmittel) https://www.gesetze-im-internet.de/btmg_1981/anlage_i.html German 6 April 2022 Substances controlled under Anlage I BtMG are illegal to manufacture, possess, import, export, buy, sell, procure or dispense without a license. Violations of the law are punishable by a fine or imprisonment for up to five years.Bundesministerium der Justiz Gesetz über den Verkehr mit Betäubungsmitteln (Betäubungsmittelgesetz – BtMG) § 29 Straftaten https://www.gesetze-im-internet.de/btmg_1981/__29.html German 6 April 2022 Ukraine As of July 2019, 2-FMA is a controlled substance in Ukraine (considered a narcotic).https://zakon.rada.gov.ua/laws/show/600-2019-%D0%BF Про внесення змін до Закону України "Про обіг в Україні наркотичних засобів, психотропних речовин, їх аналогів і прекурсорів" Verkhovna Rada of Ukraine 23 July 2019 Ukrainian 6 September 2021 https://web.archive.org/web/20210905235904/https://zakon.rada.gov.ua/laws/show/863-14 5 September 2021 live United States As a close analog of a scheduled controlled substance, Rösner P, Quednow B, Girreser U, Junge T Isomeric fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs) Forensic Science International 148 2–3 143–156 March 2005 15639609 10.1016/j.forsciint.2004.05.003 sale or possession of 2-FMA could be potentially prosecuted under the Federal Analogue Act.Federal Controlled Substance Analogue Act Summary https://www.erowid.org/psychoactives/law/analog/analog_info1.shtml Erowid Analog Law Vault See also Substituted amphetamine 2-Fluoroamphetamine 2-Fluoromethcathinone 3-Fluoromethamphetamine 3-Fluoroethamphetamine 4-Fluoromethamphetamine 4-Fluoroamphetamine 2-Methoxymethamphetamine (methoxyphenamine) 2F-MAR Borax combo References Category:Designer drugs Category:Methamphetamines Category:2-Fluorophenyl compounds Category:Norepinephrine-dopamine releasing agents