2,3-dimethylmalate lyase

Class of enzymes 2,3-dimethylmalate lyase 4.1.3.32 73562-28-4 0047529 The enzyme 2,3-dimethylmalate lyase (4.1.3.32) catalyzes the chemical reaction (2R,3S)-2,3-dimethylmalate propanoate + pyruvate This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming). Other names in common use include 2,3-dimethylmalate pyruvate-lyase, and (2R,3S)-2,3-dimethylmalate pyruvate-lyase. This enzyme participates in c5-branched dibasic acid metabolism. References 1 Pirzer P, Lill U, Eggerer H 1979 Nicotinic acid metabolism. 2,3-Dimethylmalate lyase Hoppe-Seyler's Z. Physiol. Chem. 360 1693–702 527937 12 10.1515/bchm2.1979.360.2.1693 Alhapel A, Darley DJ, Wagener N, Eckel E, Elsner N, Pierik AJ 2006 Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri Proc. Natl. Acad. Sci. U.S.A. 103 12341–6 16894175 10.1073/pnas.0601635103 33 1562527 2006PNAS..10312341A free Biology no Category:EC 4.1.3 Category:Enzymes of unknown structure