2-dehydropantolactone reductase (B-specific)

Class of enzymes 2-dehydropantolactone reductase (B-specific) 1.1.1.214 37211-75-9 0019141 In enzymology, a 2-dehydropantolactone reductase (B-specific) (1.1.1.214) is an enzyme that catalyzes the chemical reaction (R)-pantolactone + NADP+ 2-dehydropantolactone + NADPH + H+ Thus, the two substrates of this enzyme are (R)-pantolactone and NADP+, whereas its 3 products are 2-dehydropantolactone, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-pantolactone:NADP+ oxidoreductase (B-specific). Other names in common use include 2-oxopantoyl lactone reductase, 2-ketopantoyl lactone reductase, ketopantoyl lactone reductase, and 2-dehydropantoyl-lactone reductase (B-specific). References 1 Wilken DR, ((King HL Jr)), Dyar RE 1975 Ketopantoic acid and ketopantoyl lactone reductases: Stereospecificity of transfer of hydrogen from reduced nicotinamide adenine dinucleotide phosphate J. Biol. Chem. 250 2311–4 234966 6 10.1016/S0021-9258(19)41717-1 free Biology no Category:EC 1.1.1 Category:NADPH-dependent enzymes Category:Enzymes of unknown structure