2-Deoxy-scyllo-inosamine dehydrogenase

Class of enzymes 2-Deoxy-scyllo-inosamine dehydrogenase (SAM-dependent) 2-deoxy-scyllo-inosamine dehydrogenase 1.1.1.329 2-deoxy-scyllo-inosamine dehydrogenase (1.1.1.329, neoA (gene name), kanK (gene name)) is an enzyme with systematic name 2-deoxy-scyllo-inosamine:NAD(P)+ 1-oxidoreductase. Kudo F, Yamamoto Y, Yokoyama K, Eguchi T, Kakinuma K Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773 The Journal of Antibiotics 58 12 766–74 December 2005 16506694 10.1038/ja.2005.104 free Nepal KK, Oh TJ, Sohng JK Heterologous production of paromamine in Streptomyces lividans TK24 using kanamycin biosynthetic genes from Streptomyces kanamyceticus ATCC12853 Molecules and Cells 27 5 601–8 May 2009 19466609 10.1007/s10059-009-0080-5 free This enzyme catalyses the following chemical reaction 50% Q27133607 2-deoxy-scyllo-inosamine + NAD+ reversible H+ H+ Q27133591 3-amino-2,3-dideoxy-scyllo-inosose + NADH The enzyme can use the alternative cofactor, nicotinamide adenine dinucleotide phosphate and requires zinc.1.1.1.329 References External links 2-deoxy-scyllo-inosamine+dehydrogenase Biology no Category:EC 1.1.1