11-Ketodihydrotestosterone

Organic chemical compound vanc 11-Ketodihydrotestosterone.svg skin-invert-image 200px 17β-Hydroxy-5α-androstane-3,11-dione (1S,3aS,3bS,5aS,9aS,9bS,11aS)-1-Hydroxy-9a,11a-dimethyltetradecahydro-1H-cyclopenta[a]phenanthrene-7,10-dione 11-Oxodihydrotestosterone; 5α-Androstan-17β-ol-3,11-dione; 11-KDHT 32694-37-4 correct CAS correct FDA DX994972WA 9372548 11197479 1S/C19H28O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h11,13-14,16-17,22H,3-10H2,1-2H3/t11-,13-,14-,16-,17+,18-,19-/m0/s1 RSQKILYTRHKUIJ-HZGXJFKTSA-N C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@H]4O)C 19 28 3 304.43 g/mol 11-Ketodihydrotestosterone (11-KDHT), also known as 5α-androstan-17β-ol-3,11-dione, is an endogenous, naturally occurring steroid and androgen prohormone that is produced primarily, if not exclusively, in the adrenal glands. Pretorius E, Arlt W, Storbeck KH A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids Molecular and Cellular Endocrinology 441 76–85 February 2017 27519632 10.1016/j.mce.2016.08.014 4079662 http://pure-oai.bham.ac.uk/ws/files/30346231/Pretorius_et_al_manuscript.pdf It is closely related to 11β-hydroxyandrostenedione (11β-KA4), adrenosterone (11-ketoandrostenedione; 11-KA4), and 11-ketotestosterone (11-KT), which are also produced in the adrenal glands. See also Dihydrotestosterone 11β-Hydroxydihydrotestosterone References Category:5α-Reduced steroid metabolites Category:Secondary alcohols Category:Androgens Category:Androstanes Category:Hormones of the suprarenal cortex Category:Ketones Category:Sex hormones Category:Steroid hormones