(KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase

Class of enzymes (KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase 2.4.99.13 (KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (2.4.99.13, KDO transferase, waaA (gene), kdtA (gene), Kdo transferase, 3-deoxy-D-manno-oct-2-ulosonic acid transferase, 3-deoxy-manno-octulosonic acid transferase) is an enzyme with systematic name CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase. Belunis CJ, Raetz CR Biosynthesis of endotoxins. Purification and catalytic properties of 3-deoxy-D-manno-octulosonic acid transferase from Escherichia coli The Journal of Biological Chemistry 267 14 9988–97 May 1992 10.1016/S0021-9258(19)50189-2 free 1577828 Löbau S, Mamat U, Brabetz W, Brade H Molecular cloning, sequence analysis, and functional characterization of the lipopolysaccharide biosynthetic gene kdtA encoding 3-deoxy-alpha-D-manno-octulosonic acid transferase of Chlamydia pneumoniae strain TW-183 Molecular Microbiology 18 3 391–9 November 1995 8748024 10.1111/j.1365-2958.1995.mmi_18030391.x This enzyme catalyses the following chemical reaction alpha-Kdo-(2->6)-lipid IVA + CMP-alpha-Kdo alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP The bifunctional enzyme from Escherichia coli transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA. See also EC 2.4.99.12, lipid IVA 3-deoxy-D-manno-octulosonic acid transferase References External links (KDO)-lipid+IVA+3-deoxy-D-manno-octulosonic+acid+transferase Biology no Category:EC 2.4.99