2-haloacid dehalogenase (configuration-retaining)

Class of enzymes 2-haloacid dehalogenase (configuration-retaining) 3.8.1.11 2-haloacid dehalogenase (configuration-retaining) (3.8.1.11, 2-haloalkanoic acid dehalogenase, 2-haloalkanoid acid halidohydrolase, DL-2-haloacid dehalogenase, DL-DEXr) is an enzyme with systematic name (S)-2-haloacid dehalogenase (configuration-retaining). Weightman AJ, Weightman AL, Slater JH Stereospecificity of 2-monochloropropionate dehalogenation by the two dehalogenases of Pseudomonas putida PP3: evidence for two different dehalogenation mechanisms Journal of General Microbiology 128 8 1755–62 August 1982 7142958 10.1099/00221287-128-8-1755 free Bacterial 2-haloacid dehalogenases: Structures and catalytic properties Soda, K. Kurihara, T. Liu, J.-Q. Nardi-Dei, V. Park, C. Miyagi, M. Tsunasawa, S. Esaki, N. Pure Appl. Chem. 1996 68 11 2097–2103 10.1351/pac199668112097 free This enzyme catalyses the following chemical reaction (1) (S)-2-haloacid + H2O (S)-2-hydroxyacid + halide (2) (R)-2-haloacid + H2O (R)-2-hydroxyacid + halide Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the corresponding (S)- and (R)-hydroxyalkanoic acids. References External links 2-haloacid+dehalogenase+(configuration-retaining) Biology no Category:EC 3.8.1