(−)-beta-pinene synthase

Enzyme (−)-β-pinene synthase 4.2.3.120 (−)-β-Pinene synthase (EC 4.2.3.120, β-geraniolene synthase, (−)-(1S,5S)-pinene synthase, geranyldiphosphate diphosphate lyase (pinene forming)) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase [cyclizing, (−)-β-pinene-forming]. Croteau RB, Wheeler CJ, Cane DE, Ebert R, Ha HJ Isotopically sensitive branching in the formation of cyclic monoterpenes: proof that (−)-α-pinene and (−)-β-pinene are synthesized by the same monoterpene cyclase via deprotonation of a common intermediate Biochemistry 26 17 5383–9 August 1987 3314988 10.1021/bi00391a025 Croteau R, Satterwhite DM Biosynthesis of monoterpenes. Stereochemical implications of acyclic and monocyclic olefin formation by (+)- and (−)-pinene cyclases from sage The Journal of Biological Chemistry 264 26 15309–15 September 1989 10.1016/S0021-9258(19)84827-5 free 2768265 Croteau R, Satterwhite DM, Cane DE, Chang CC Biosynthesis of monoterpenes. Enantioselectivity in the enzymatic cyclization of (+)- and (−)-linalyl pyrophosphate to (+)- and (−)-pinene and (+)- and (−)-camphene The Journal of Biological Chemistry 263 21 10063–71 July 1988 10.1016/S0021-9258(19)81477-1 free 3392006 Pyun HJ, Wagschal KC, Jung DI, Coates RM, Croteau R Stereochemistry of the proton elimination in the formation of (+)- and (−)-α-pinene by monoterpene cyclases from sage (Salvia officinalis) Archives of Biochemistry and Biophysics 308 2 488–96 February 1994 8109979 10.1006/abbi.1994.1069 Lu S, Xu R, Jia JW, Pang J, Matsuda SP, Chen XY Cloning and functional characterization of a β-pinene synthase from Artemisia annua that shows a circadian pattern of expression Plant Physiology 130 1 477–86 September 2002 12226526 166579 10.1104/pp.006544 Gijzen M, Lewinsohn E, Croteau R Characterization of the constitutive and wound-inducible monoterpene cyclases of grand fir (Abies grandis) Archives of Biochemistry and Biophysics 289 2 267–73 September 1991 1898071 10.1016/0003-9861(91)90471-T Lewinsohn E, Gijzen M, Croteau R Wound-inducible pinene cyclase from grand fir: purification, characterization, and renaturation after SDS-PAGE Archives of Biochemistry and Biophysics 293 1 167–73 February 1992 1731633 10.1016/0003-9861(92)90380-f Bohlmann J, Steele CL, Croteau R Monoterpene synthases from grand fir (Abies grandis). cDNA isolation, characterization, and functional expression of myrcene synthase, (−)-(4S)-limonene synthase, and (−)-(1S,5S)-pinene synthase The Journal of Biological Chemistry 272 35 21784–92 August 1997 9268308 10.1074/jbc.272.35.21784 free Hyatt DC, Croteau R Mutational analysis of a monoterpene synthase reaction: altered catalysis through directed mutagenesis of (−)-pinene synthase from Abies grandis Archives of Biochemistry and Biophysics 439 2 222–33 July 2005 15978541 10.1016/j.abb.2005.05.017 Savage TJ, Ichii H, Hume SD, Little DB, Croteau R Monoterpene synthases from gymnosperms and angiosperms: stereospecificity and inactivation by cysteinyl- and arginyl-directed modifying reagents Archives of Biochemistry and Biophysics 320 2 257–65 July 1995 7625832 10.1016/0003-9861(95)90008-x Phillips MA, Savage TJ, Croteau R Monoterpene synthases of loblolly pine (Pinus taeda) produce pinene isomers and enantiomers Archives of Biochemistry and Biophysics 372 1 197–204 December 1999 10562434 10.1006/abbi.1999.1467 McKay SA, Hunter WL, Godard KA, Wang SX, Martin DM, Bohlmann J, Plant AL Insect attack and wounding induce traumatic resin duct development and gene expression of (−)-pinene synthase in Sitka spruce Plant Physiology 133 1 368–78 September 2003 12970502 196613 10.1104/pp.103.022723 This enzyme catalyses the following chemical reaction geranyl diphosphate (−)-β-pinene + diphosphate Cyclase II of Salvia officinalis (sage) produces about equal parts (−)-α-pinene, (−)-β-pinene and (−)-camphene. References External links (−)-beta-pinene+synthase Biology no Category:EC 4.2.3