150 Milligrams

2016 film January 2018 150 Milligrams La Fille de Brest.jpg Theatrical release poster Emmanuelle Bercot Caroline BenjoCarole Scotta Séverine BosschemEmmanuelle BercotRomain Compingt Mediator 150 mg Irène Frachon Sidse Babett KnudsenBenoît Magimel Martin Wheeler Guillaume Schiffman Julien Leloup Haut et Court 2016 9 12 TIFF 2016 11 23 France yes 128 minutes France French $6.1 millionhttp://www.jpbox-office.com/fichfilm.php?id=16408 La Fille de Brest (2016)- JPBox-Office JP 7 January 2017 $2.9 millionhttps://www.boxofficemojo.com/movies/intl/?id=_fLAFILLEDEBREST01&country=FR&wk=2016W48&id=_fLAFILLEDEBREST01&p=.htm La fille de Brest www.boxofficemojo.com 26 February 2019 150 Milligrams (fr La Fille de Brest, lit. The Girl of Brest) is a 2016 French drama film directed by Emmanuelle Bercot.http://www.hollywoodreporter.com/news/emmanuelle-bercot-open-san-sebastian-922419 Emmanuelle Bercot's '150 Milligrams' to Open San Sebastian Festival 25 August 2016 The Hollywood Reporter 24 August 2016 It was screened in the Special Presentations section at the 2016 Toronto International Film Festival.http://www.screendaily.com/festivals/toronto/toronto-unveils-city-to-city-world-cinema-masters-line-ups/5108484.article Toronto unveils City To City, World Cinema, Masters line-ups 22 August 2016 ScreenDaily The film is based on the true story of French pulmonologist Irène Frachon fr, who became noted for her investigations of the serious side effects and deaths attributed to the diabetes drug Mediator, produced by French manufacturer Laboratoires Servier.Felperin Leslie http://www.hollywoodreporter.com/review/150-milligrams-review-932506 '150 Milligrams' ('La Fille de Brest'): Film Review The Hollywood Reporter 26 September 2016 18 November 2016 Plot Sidse Babett Knudsen portrays real-life whistleblower Dr. Irene Frachon, a specialist in pulmonology. The story is set in the university hospital in Brest, Northern France. The film opens with doctors performing open-heart surgery. Dr. Irene observes that the heart valves of a patient, Corinne Zacharria, appear severely damaged. This condition has been detected in multiple patients, all of whom consumed Mediator, a drug manufactured by the French pharmaceutical firm Servier, intended for diabetes treatment and weight loss. Dr. Irene believes Mediator is causing the pathology. To confirm this, she requires evidence from a proper epidemiological study. Several of her colleagues collaborate on this, but the contribution of research scientist Dr. Antoine Le Bihan is especially significant. Their research findings strongly support Irene's hypothesis. However, when presenting their findings to AFSSAPS, the French regulatory agency for health products, their research is intensely scrutinized by Servier's representatives, and they're unsuccessful in getting Mediator removed from the market. Despite feeling disheartened, Irene continues her fight, getting support from various individuals. She self-publishes a book on their research, with Servier attempting to halt its publication. Irene gets support from her family, a reporter from Le Figaro, Anne Jouan, an AFSSAPS member, Catherine Haynes, and an informant from CNAM, the national health insurance fund. The investigation reveals around 500 deaths connected to the drug, predominantly women. Cast Sidse Babett Knudsen as Irène Frachon fr Benoît Magimel as Antoine Le Bihan Charlotte Laemmel as Patoche Lara Neumann as Anne Jouan Philippe Uchan fr Philippe Uchan as Aubert Patrick Ligardes fr Patrick Ligardes as Bruno Frachon Olivier Pasquier as Arsène Weber Isabelle de Hertogh as Corinne Zacharria Gustave Kervern as Kermarec Pablo Pauly as Charles-Joseph Oudin Myriam Azencot as Catherine Haynes Eddie Chignara as Christophe Laugier Raphaël Ferret as Fred Christophe Meynet as David Gilles Treton fr Gilles Treton as Yannick Jobic Élise Lucet as herself Reception The Hollywood Reporter's Leslie Felperin cited the "outsize but empathic central performance" by star Sidse Babett Knudsen in the role of Frachon and the director's ability to handle the film's "intellectually rigorous storytelling" and many characters. Accolades Award / Film FestivalCategoryRecipients and nomineesResultCésar AwardsBest ActressSidse Babett Knudsen Best AdaptationSéverine Bosschem and Emmanuelle Bercot Magritte AwardsBest Supporting ActressIsabelle de Hertogh Lumière AwardsBest ActressSidse Babett Knudsen See also List of films featuring diabetes References External links 5247544 150 Milligrams Category:2016 films Category:2016 drama films Category:2016 French-language films Category:Biographical films about medical doctors Category:Drama films based on actual events Category:French drama films Category:Films about medical malpractice Category:Films based on non-fiction books Category:Medical-themed films Category:Films directed by Emmanuelle Bercot Category:2016 French films Category:French-language drama films Category:French films based on actual events Category:Works about diabetes