2,4-dienoyl-CoA reductase 1

Protein-coding gene in the species Homo sapiens vanc 2,4-dienoyl-CoA reductase 1 is a protein that in humans is encoded by the DECR1 gene.Entrez Gene: 2,4-dienoyl-CoA reductase 1 https://www.ncbi.nlm.nih.gov/gene/1666 2017-09-12 Function This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. See also DECR2 References Further reading 30em Alphey MS, Yu W, Byres E, Li D, Hunter WN Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site J. Biol. Chem. 280 4 3068–77 2005 15531764 10.1074/jbc.M411069200 free Yu W, Chu X, Chen G, Li D Studies of human mitochondrial 2,4-dienoyl-CoA reductase Arch. Biochem. Biophys. 434 1 195–200 2005 15629123 10.1016/j.abb.2004.10.018 Rosenzweig SD Inflammatory manifestations in chronic granulomatous disease (CGD) J. Clin. Immunol. 28 S67–72 2008 Suppl 1 18193341 10.1007/s10875-007-9160-5 5965278 Kardon T, Senesi S, Marcolongo P, Legeza B, Bánhegyi G, Mandl J, Fulceri R, Benedetti A Maintenance of luminal NADPH in the endoplasmic reticulum promotes the survival of human neutrophil granulocytes FEBS Lett. 582 13 1809–15 2008 18472006 10.1016/j.febslet.2008.04.045 2008FEBSL.582.1809K 41166916 free Mizuta I, Tsunoda T, Satake W, Nakabayashi Y, Watanabe M, Takeda A, Hasegawa K, Nakashima K, Yamamoto M, Hattori N, Murata M, Toda T Calbindin 1, fibroblast growth factor 20, and alpha-synuclein in sporadic Parkinson's disease Hum. Genet. 124 1 89–94 2008 18568448 10.1007/s00439-008-0525-5 20604147 Moe KT, Woon FP, De Silva DA, Wong P, Koh TH, Kingwell B, Chin-Dusting J, Wong MC Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population Eur. J. Neurol. 15 12 1309–14 2008 19049547 10.1111/j.1468-1331.2008.02308.x 10457617 Hosgood HD, Zhang L, Shen M, Berndt SI, Vermeulen R, Li G, Yin S, Yeager M, Yuenger J, Rothman N, Chanock S, Smith M, Lan Q Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity Occup Environ Med 66 12 848–53 2009 19773279 2928224 10.1136/oem.2008.044024 Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score Mol. Med. 16 7–8 247–53 2010 20379614 2896464 10.2119/molmed.2009.00159 Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression PLOS ONE 5 9 e12862 2010 20877624 2943476 10.1371/journal.pone.0012862 2010PLoSO...512862H free *