1,3-Benzodioxole

changed changed 477204881 Benzo(d)(1,3)dioxole 200.svg skin-invert-image correct ?? Kekulé, skeletal formula of 1,3-benzodioxole 1,3-Benzodioxole-3D-balls.png bg-transparent correct ?? Ball and stick model of 1,3-benzodioxole 2H-1,3-Benzodioxole 1,3-BenzodioxoleBenzo[d][1,3]dioxole1,2-[Methylenebis(oxy)]benzene1,2-Methylenedioxybenzene correct CAS 274-09-9 correct FDA F0XLL582B8 9229 13881169 correct chemspider 205-992-0 1993 1,3-Benzodioxole correct EBI 38732 DA5600000 115506 C1Oc2ccccc2O1 C1OC2=C(O1)C=CC=C2 1S/C7H6O2/c1-2-4-7-6(3-1)8-5-9-7/h1-4H,5H2 correct chemspider 1/C7H6O2/c1-2-4-7-6(3-1)8-5-9-7/h1-4H,5H2 FTNJQNQLEGKTGD-UHFFFAOYSA-N correct chemspider FTNJQNQLEGKTGD-UHFFFAOYAV 7 6 2 1.064 g cm−3 172-173 2.08 1.6 kPa −3.428 MJ mol−1 exclamation mark WARNING 302 332 2 1 0 61 1,3-Benzodioxole (1,2-methylenedioxybenzene) is an organic compound with the formula C6H4O2CH2. The compound is classified as benzene derivative and a heterocyclic compound containing the methylenedioxy functional group. It is a colorless liquid. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Murray, M., "Mechanisms of inhibitory and regulatory effects of methylenedioxyphenyl compounds on cytochrome P450-dependent drug oxidation", Curr. Drug Metab. 2000, volume 1, 67-84. 10.2174/1389200003339270 Preparation 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Bonthrone, W. Cornforth, J. amp The methylenation of catechols Journal of the Chemical Society 9 1969 1202–1204 10.1039/J39690001202 http://pubs.rsc.org/en/content/articlelanding/1969/J3/j39690001202 28 December 2013 subscriptionFujita, Harushige Yamashita amp Masataro The Methylenation of Several Allylbenzene-1,2-diol Derivatives in Aprotic Polar Solvents Bulletin of the Chemical Society of Japan 1973 46 11 3553–3554 10.1246/bcsj.46.3553 https://www.jstage.jst.go.jp/article/bcsj1926/46/11/46_11_3553/_article 27 December 2013 free 10 May 2023 https://web.archive.org/web/20230510013813/https://www.jstage.jst.go.jp/article/bcsj1926/46/11/46_11_3553/_article dead See also 1,4-Benzodioxine MDMA Methylenedioxy Safrole Piperonal Piperonyl butoxide and sesamex are benzodioxole-based adjuvants, used to enhance the efficacy of some insecticidesMetcalf Deceased Robert L. Horowitz Abraham Rami Ullmann's Encyclopedia of Industrial Chemistry Insect Control, 2. Individual Insecticides 2014 1–94 10.1002/14356007.s14_s01 978-3-527-30673-2 References