(+)-epicubenol synthase

Class of enzymes (+)-epicubenol synthase 4.2.3.64 (+)-Epicubenol synthase (EC 4.2.3.64, farnesyl pyrophosphate cyclase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-epicubenol-forming). Cane DE, Tandon M, Prabhakaran PC Epicubenol synthase and the enzymatic cyclization of farnesyl diphosphate J. Am. Chem. Soc. 1993 115 18 8103–8106 10.1021/ja00071a023 1993JAChS.115.8103C Cane DE, Tandon M Biosynthesis of (+)-epicubenol. Tetrahedron Lett. 1994 35 30 5355–5358 10.1016/s0040-4039(00)73498-8 Cane DE, Tandon M Epicubenol synthase and the stereochemistry of the enzymatic cyclization of farnesyl and nerolidyl diphosphate J. Am. Chem. Soc. 1995 117 20 5602–5603 10.1021/ja00125a029 1995JAChS.117.5602C Nabeta K, Kigure K, Fujita M, Nagoya T, Ishikawa T, Okuyama H, Takasawa T Bioynthesis of (+)-cubenene and (+)-epicubenol by cell-free extracts of cultured cells of Heteroscyphus planus and cyclization of [2H]farnesyl diphosphates J. Chem. Soc., Perkin Trans. 1 1995 15 1935–1939 10.1039/p19950001935 Nabeta K, Fujita M, Komuro K, Katayama K, Takasawa T In vitro biosynthesis of cadinanes by cell-free extracts of cultured cells of Heteroscyphus planus J. Chem. Soc., Perkin Trans. 1 1997 14 2065–2070 10.1039/a701145h This enzyme catalyses the following chemical reaction (2E,6E)-farnesyl diphosphate + H2O (+)-epicubenol + diphosphate This enzyme requires Mg2+. References External links (+)-epicubenol+synthase Biology no Category:EC 4.2.3