2-oxobutyrate synthase

Class of enzymes 2-oxobutyrate synthase 1.2.7.2 37251-04-0 0018491 In enzymology, a 2-oxobutyrate synthase (1.2.7.2) is an enzyme that catalyzes the chemical reaction 2-oxobutanoate + CoA + oxidized ferredoxin propanoyl-CoA + CO2 + reduced ferredoxin The 3 substrates of this enzyme are 2-oxobutanoate, CoA, and oxidized ferredoxin, whereas its 3 products are propanoyl-CoA, CO2, and reduced ferredoxin. This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propanoylating). Other names in common use include alpha-ketobutyrate-ferredoxin oxidoreductase, 2-ketobutyrate synthase, alpha-ketobutyrate synthase, 2-oxobutyrate-ferredoxin oxidoreductase, and 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating). This enzyme participates in propanoate metabolism. References Buchanan BB Role of ferredoxin in the synthesis of alpha-ketobutyrate from propionyl coenzyme A and carbon dioxide by enzymes from photosynthetic and nonphotosynthetic bacteria The Journal of Biological Chemistry 244 15 4218–23 August 1969 10.1016/S0021-9258(17)36404-9 free 5800441 Biology no Category:EC 1.2.7 Category:Enzymes of unknown structure