2-Phenylbenzofuran

Chemical compound 2-Phenylbenzofuran.svg 2-Phenyl-1-benzofuran 1839-72-1 654-035-7 1643182 2757343 3517936 1S/C14H10O/c1-2-6-11(7-3-1)14-10-12-8-4-5-9-13(12)15-14/h1-10H HXMZLDUBSSPQIB-UHFFFAOYSA-N C1=CC=C(C=C1)C2=CC3=CC=CC=C3O2 14 10 1 https://pubchem.ncbi.nlm.nih.gov/compound/2-Phenylbenzofuran 2-Phenylbenzofuran National Library of Medicine September 8, 2005 PubChem June 10, 2024 07 Warning 302 413 264 270 273 301+317 330 501 2-Phenylbenzofuran (2-phenyl-benzo[b]furan) is a chemical compound that has the molecular formula C14H10O. It is a substituted benzofuran, with a phenyl group as the substituent. Occurrence and synthesis 2-Phenylbenzofuran is a natural product, and its derivatives (known as 2-phenylbenzofurans) have been isolated from various plants, such as Artocarpus pithecogallus,Thuy Phan Thi Trang Nguyen Van Son Ninh The 2020-02-07 Antioxidation of 2-phenylbenzofuran derivatives: structural-electronic effects and mechanisms RSC Advances en 10 11 6315–6332 10.1039/C9RA10835A 35496026 9049690 2020RSCAd..10.6315T 2046-2069 legumes, and mulberries.Kinoshita Takeshi Ichinose Koji 2005-10-25 A Short-Step Convenient Synthesis of 2-Phenylbenzofuran from 3-Phenylcoumarin. https://library.navoiy-uni.uz/files/takeshi%20kinoshita%20and%20koji%20ichinose.%20%20a%20short%20step%20convenient%20synthesis%20of%202-phenylbenzofuran%20from%203-phentlcoumarin.pdf ChemInform en 36 43 10.1002/chin.200543118 0931-7597 2024-06-10 2024-06-10 https://web.archive.org/web/20240610144627/https://library.navoiy-uni.uz/files/takeshi%20kinoshita%20and%20koji%20ichinose.%20%20a%20short%20step%20convenient%20synthesis%20of%202-phenylbenzofuran%20from%203-phentlcoumarin.pdf dead Wang Wen Wu Dong-Ling Liao Sen-Tai Fan Chun-Lin Guo-Qiang Li Zhang Xian-Tao Wang Ying Zhang Xiao-Qi Ye Wen-Cai May 2013 Two 2-Phenylbenzofuran Derivatives from Morus atropurpurea Natural Product Communications 8 5 599–600 10.1177/1934578X1300800514 Because there is a substituent at position 2, this benzofuran compound cannot be synthesized by the Perkin rearrangement from a coumarin. However, an alternate sequence has been demonstrated: treatment of 3-phenylcoumarin with aluminium hydride followed by DDQ: File:3mthcmrn-2phenbenzf.png Applications 2-Phenylbenzofuran and its derivatives have been the subject of research on antioxidant drugs,Borges Rosivaldo S. Aguiar Christiane P. O. Oliveira Nicole L. L. Amaral Israel N. A. Vale Joyce K. L. Chaves Neto Antonio M. J. Queiroz Auriekson N. da Silva Albérico B. F. August 2023 Antioxidant capacity of simplified oxygen heterocycles and proposed derivatives by theoretical calculations Journal of Molecular Modeling en 29 8 10.1007/s00894-023-05602-8 1610-2940 butyrylcholinesterase inhibition, Giovanna L. Delogu Maria J. Matos Maura Fanti Benedetta Era Rosaria Medda Enrico Pieroni Antonella Fais Amit Kumar Francesca Pintus 2-Phenylbenzofuran derivatives as butyrylcholinesterase inhibitors: Synthesis, biological activity and molecular modeling Bioorganic & Medicinal Chemistry Letters 2016 26 9 2308–2313 en 10.1016/j.bmcl.2016.03.039 26995529 and leishmaniasis treatment.Agarwal A. A QSAR Study Investigating the Potential Anti-Leishmanial Activity of Cationic 2-Phenylbenzofurans 2012 Chemistry of Phytopotentials: Health, Energy and Environmental Perspectives 137–141 Khemani L. D. Berlin, Heidelberg Springer Berlin Heidelberg en 10.1007/978-3-642-23394-4_30 978-3-642-23393-7 Mishra R. Paliwal S. Srivastava M. M. Srivastava Shalini References Category:Benzofurans