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2,3,5,6-Tetramethoxyamphetamine
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TeMA-3 2,3,5,6-Tetramethoxyamphetamine.svg skin-invert-image 225px None 23693-28-9 2,3,5,6-TeMA; TeMA-3 1-(2,3,5,6-tetramethoxyphenyl)propan-2-amine 13 21 1 4 COc1cc(OC)c(c(c1OC)CC(N)C)OC 1S/C13H21NO4/c1-8(14)6-9-12(17-4)10(15-2)7-11(16-3)13(9)18-5/h7-8H,6,14H2,1-5H3 UMWIVVHAMHPTBF-UHFFFAOYSA-N
2,3,5,6-Tetramethoxyamphetamine (2,3,5,6-TeMA), also known as TeMA-3, is a chemical compound of the phenethylamine and amphetamine families related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). Shulgin A, Manning T, Daley P The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds Berkeley 1 xix, 282 2011 Transform Press 978-0-9630096-3-0 Trachsel D, Lehmann D, Enzensperger C Phenethylamine: von der Struktur zur Funktion Solothurn 930–931 2013 Phenethylamines: From Structure to Function 1 Nachtschatten-Verlag Nachtschatten-Science 978-3-03788-700-4 858805226 https://books.google.com/books?id=-Us1kgEACAAJ de Shulgin AT, Sargent T, Naranjo C Structure--activity relationships of one-ring psychotomimetics Nature 221 5180 537–541 February 1969 5789297 10.1038/221537a0 1969Natur.221..537S It was first described in the scientific literature by Alexander Shulgin and colleagues in 1969, but had not been synthesized or assessed by them at that time. The fluorescence of TeMA-3 has been studied. Antun F, Smythies JR, Benington F, Morin RD, Barfknecht CF, Nichols DE Native fluorescence and hallucinogenic potency of some amphetamines Experientia 27 1 62–63 January 1971 5549244 10.1007/BF02137743 Very little appears to be known about TeMA-3. It is a controlled substance in Canada under phenethylamine blanket-ban language.Controlled Drugs and Substances Act Department of Justice Canada https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html 19 January 2026
See also
Substituted methoxyphenethylamine
Tetramethoxyamphetamine
Tetramethoxyphenethylamine
2,3,5,6-Tetramethoxyphenethylamine
References
External links
TeMA-3 - Isomer Design
Category:Methoxyphenethylamines
Category:Substituted amphetamines