2-(S)-hydroxypropyl-CoM dehydrogenase

Class of enzymes 2-(S)-hydroxypropyl-CoM dehydrogenase 1.1.1.269 0050575 In enzymology, a 2-(S)-hydroxypropyl-CoM dehydrogenase (1.1.1.269) is an enzyme that catalyzes the chemical reaction 2-(S)-hydroxypropyl-CoM + NAD+ 2-oxopropyl-CoM + NADH + H+ Thus, the two substrates of this enzyme are 2-(S)-hydroxypropyl-CoM and NAD+, whereas its 3 products are 2-oxopropyl-CoM, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-[2-(S)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase. This enzyme is also called 2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase. References 1 Allen JR, Clark DD, Krum JG, Ensign SA 1999 A role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylation Proc. Natl. Acad. Sci. U.S.A. 96 8432–7 10411892 10.1073/pnas.96.15.8432 15 17533 1999PNAS...96.8432A free Biology no Category:EC 1.1.1 Category:NADH-dependent enzymes Category:Enzymes of unknown structure