1,3-propanediol dehydrogenase

Class of enzymesJuly 2025 1,3-propanediol dehydrogenase 1.1.1.202 81611-70-3 0047516 In enzymology, a 1,3-propanediol dehydrogenase (1.1.1.202) is an enzyme that catalyzes the chemical reaction propane-1,3-diol + NAD+ 3-hydroxypropanal + NADH + H+ Thus, the two substrates of this enzyme are propane-1,3-diol and NAD+, whereas its 3 products are 3-hydroxypropanal, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propane-1,3-diol:NAD+ 1-oxidoreductase. Other names in common use include 3-hydroxypropionaldehyde reductase, 1,3-PD:NAD+ oxidoreductase, 1,3-propanediol:NAD+ oxidoreductase, and 1,3-propanediol dehydrogenase. This enzyme participates in ether lipid metabolism as a step in glycerolipid biosynthesis. References 1 Abeles RH, Brownstein AM, Randles CH 1960 beta-Hydroxypropionaldehyde, an intermediate in the formation of 1,3-propanediol by Aerobacter aerogenes Biochim. Biophys. Acta 41 530–1 13791444 10.1016/0006-3002(60)90054-8 3 Forage RG, Foster MA 1982 Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases J. Bacteriol. 149 413–9 7035429 2 10.1128/JB.149.2.413-419.1982 216523 Biology no Category:EC 1.1.1 Category:NADH-dependent enzymes Category:Enzymes of known structure