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1-Iodohexane
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1-Iodohexane Hexyl iodide.svg 1-Iodohexane 1-Hexyl iodide 638-45-9 correct CAS 12527 27F4BFU2DR 3188734 12010 211-339-0 DTXSID2049341 1S/C6H13I/c1-2-3-4-5-6-7/h2-6H2,1H3 ANOOTOPTCJRUPK-UHFFFAOYSA-N CCCCCCI
6 13 1 yellowish liquid 1.437 g/cm3 practically insoluble -75 181
1-Iodohexane https://pubchem.ncbi.nlm.nih.gov/compound/12527#section=Safety-and-Hazards pubchem.ncbi.nlm.nih.gov en 05 07 Danger 302 315 318 319 335 261 264 264+265 270 271 280 301+317 302+352 304+340 305+351+338 305+354+338 317 319 321 330 332+317 337+317 362+364 403+233 405 501
1-Bromohexane1-Chlorohexane1-Fluorohexane
1-Iodohexane is a chemical compound from the group of aliphatic saturated halogenated hydrocarbons. The chemical formula is CH3(CH2)5I.Hexane, 1-iodo- https://webbook.nist.gov/cgi/cbook.cgi?ID=638-45-9 NIST 8 August 2024Barnes Ian Rudzinski Krzysztof J. Environmental Simulation Chambers: Application to Atmospheric Chemical Processes 13 January 2006 Springer Science & Business Media 978-1-4020-4231-7 202 https://books.google.com/books?id=H5NvQHm4RV4C&dq=1-Iodohexane&pg=PA202 8 August 2024 en It is a colorless liquid.
Synthesis
1-Iodohexane can be obtained by treating 1-bromohexane with potassium iodide.Hernán-Gómez Alberto Rodríguez Mònica Parella Teodor Costas Miquel Electrophilic Iron Catalyst Paired with a Lithium Cation Enables Selective Functionalization of Non-Activated Aliphatic C−H Bonds via Metallocarbene Intermediates Angewandte Chemie International Edition 23 September 2019 58 39 13904–13911 10.1002/anie.201905986 31338944 https://onlinelibrary.wiley.com/doi/10.1002/anie.201905986 8 August 2024 en 1433-7851 subscription
The compound can also be prepared by treating 1-hexanol with iodine and triphenylphosphine.Alberto Hernán-Gómez, Mònica Rodríguez, Teodor Parella, Miquel Costas. Electrophilic Iron Catalyst Paired with a Lithium Cation Enables Selective Functionalization of Non-Activated Aliphatic C−H Bonds via Metallocarbene Intermediates. Angew Chem Int Ed, 2019. 58 (39): 13904-13911. 10.1002/anie.201905986.
Physical properties
1-Iodohexane is a flammable, difficult to ignite, light-sensitive liquid that is practically insoluble in water.Marine enzymes and specialized metabolism - Part B 22 June 2018 Academic Press 978-0-12-815046-7 212 https://books.google.com/books?id=m11gDwAAQBAJ&dq=1-Iodohexane&pg=PA212 8 August 2024 en Copper is usually added to the compound as a stabilizer.1-Iodohexane https://www.sigmaaldrich.com/RU/en/product/aldrich/238287 Sigma Aldrich 8 August 2024
Uses
The compound is used as an alkylating agent in organic synthesis.1-Iodohexane CAS 638-45-9 SCBT - Santa Cruz Biotechnology https://www.scbt.com/p/1-iodohexane-638-45-9 scbt.com 8 August 2024 en Also, it is used as an intermediate in the production of other chemical compounds such as tetradecane.
See also
1-Bromohexane
1-Chlorohexane
1-Fluorohexane
References
Category:Iodoalkanes
Category:Alkylating agents