2-hydroxyglutarate synthase

Class of enzymes 2-hydroxyglutarate synthase 2.3.3.11 9024-02-6 0019142 2-hydroxyglutarate synthase (2.3.3.11) is an enzyme that catalyzes the chemical reaction 70% Glyoxylic acid 0.6 + Propanoyl-CoA H2O α-Hydroxyglutaric acid + Coenzyme A The three substrates of this enzyme are glyoxylic acid, propanoyl-CoA, and water. Its products are α-hydroxyglutaric acid and coenzyme A. Reeves HC, Ajl SJ Alpha-hydroxyglutaric acid synthetase Journal of Bacteriology 84 186–7 July 1962 1 10.1128/jb.84.1.186-187.1962 14491016 277798 This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. The systematic name of this enzyme class is propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming). Other names in common use include 2-hydroxyglutaratic synthetase, 2-hydroxyglutaric synthetase, alpha-hydroxyglutarate synthase, hydroxyglutarate synthase, and 2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating).2.3.3.11 See also D2HGDH L2HGDH 2-hydroxyglutarate dehydrogenase 2-Hydroxyglutaric aciduria Hydroxyacid-oxoacid transhydrogenase References Biology no Category:EC 2.3.3 Category:Enzymes of unknown structure