(cytochrome c)-lysine N-methyltransferase

Class of enzymes [cytochrome c]-lysine N-methyltransferase 2.1.1.59 82047-78-7 0000277 In enzymology, a [cytochrome c]-lysine N-methyltransferase (2.1.1.59) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + [cytochrome c]-L-lysine S-adenosyl-L-homocysteine + [cytochrome c]-N6-methyl-L-lysine Thus, the two substrates of this enzyme are S-adenosyl methionine and cytochrome c-L-lysine, whereas its two products are S-adenosylhomocysteine and cytochrome c-N6-methyl-L-lysine. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:[cytochrome c]-L-lysine N6-methyltransferase. Other names in common use include cytochrome c (lysine) methyltransferase, cytochrome c methyltransferase, cytochrome c-specific protein methylase III, cytochrome c-specific protein-lysine methyltransferase, S-adenosyl-L-methionine:[cytochrome c]-L-lysine, and 6-N-methyltransferase. This enzyme participates in lysine degradation. References 1 Durban E, Nochumson S, Kim S, Paik WK, Chan SK 1978 Cytochrome c-specific protein-lysine methyltransferase from Neurospora crassa. Purification, characterization, and substrate requirements J. Biol. Chem. 253 1427–35 203592 5 10.1016/S0021-9258(17)34884-6 free Nochumson S, Durban E, Kim S, Paik WK 1977 Cytochrome c-specific protein methylase III from Neurospora crassa Biochem. J. 165 11–8 196592 1 10.1042/bj1650011 1164862 Valentine J, Pettigrew GW 1982 A cytochrome c methyltransferase from Crithidia oncopelti Biochem. J. 201 329–38 6282265 2 10.1042/bj2010329 1163647 Biology no Category:EC 2.1.1 Category:Enzymes of unknown structure