(S)-corytuberine synthase

Class of enzymes (S)-corytuberine synthase 1.14.19.51 (S)-corytuberine synthase is an enzyme purified from the plant Coptis japonica (Japanese goldthread), Ikezawa N, Iwasa K, Sato F Molecular cloning and characterization of CYP80G2, a cytochrome P450 that catalyzes an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis, from cultured Coptis japonica cells The Journal of Biological Chemistry 283 14 8810–21 April 2008 18230623 10.1074/jbc.M705082200 2008JBiCh.283.8810I free with EC number 1.14.19.51 and CYP Symbol CYP80G2. It catalyses an intramolecular C-C phenol coupling of (S)-reticuline to (S)-corytuberine in a pathway leading to magnoflorine. Meelaph T, Kobtrakul K, Chansilpa NN, Han Y, Rani D, De-Eknamkul W, Vimolmangkang S Coregulation of Biosynthetic Genes and Transcription Factors for Aporphine-Type Alkaloid Production in Wounded Lotus Provides Insight into the Biosynthetic Pathway of Nuciferine ACS Omega 3 8 8794–8802 August 2018 31459012 10.1021/acsomega.8b00827 6644620 free Tian Y, Kong L, Li Q, Wang Y, Wang Y, An Z, Ma Y, Tian L, Duan B, Sun W, Gao R, Chen S, Xu Z Structural diversity, evolutionary origin, and metabolic engineering of plant specialized benzylisoquinoline alkaloids Natural Product Reports 41 11 1787–1810 November 2024 39360417 10.1039/d4np00029c 65% reticuline (S)-reticuline + NADPH O2 2 H2O Q27155145 (S)-corytuberine + NADP+ (S)-corytuberine synthase is a cytochrome P450 protein containing heme. It requires a partner cytochrome P450 reductase for functional expression. This uses nicotinamide adenine dinucleotide phosphate (NADPH).1.14.19.51 References Category:EC 1.14.19 Category:Cytochrome P450 Family 80