10-hydroxydihydrosanguinarine 10-O-methyltransferase

Class of enzymes 10-hydroxydihydrosanguinarine 10-O-methyltransferase 2.1.1.119 144388-39-6 0030779 10-hydroxydihydrosanguinarine 10-O-methyltransferase (2.1.1.119) is an enzyme that catalyzes the chemical reaction 65% Q27098277 10-hydroxydihydrosanguinarine + SAM Q3707626 dihydrochelirubine + SAH This is a methylation reaction in which the benzylisoquinoline alkaloid, 10-hydroxydihydrosanguinarine, is converted to dihydrochelirubine. The methyl group comes from the cofactor, S-adenosyl methionine (SAM), which becomes S-adenosyl-L-homocysteine (SAH). The enzyme was characterised from Eschscholtzia californica.De-Eknamkul W, Tanahashi T, Zenk MH 1992 Enzymic 10-hydroxylation and 10-O-methylation of dihydrosanguinarine in dihydrochelirubine formation by Eschscholtzia https://archive.org/details/sim_phytochemistry_1992-08_31_8/page/2713 Phytochemistry 31 2713–2717 10.1016/0031-9422(92)83617-8 8 1992PChem..31.2713D This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase. It is part of the alkaloid biosynthesis pathway.2.1.1.119 References Biology no Category:EC 2.1.1 Category:Enzymes of unknown structure