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2,4-Dichlorobenzoic acid
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2,4-Dichlorbenzoesäure.svg 120px 2,4-Dichlorobenzoic acid 50-84-0 200-067-8 0SR0320D45 30748 1492029 5583 562565 C06670 5787 1S/C7H4Cl2O2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,(H,10,11) ATCRIUVQKHMXSH-UHFFFAOYSA-N C1=CC(=C(C=C1Cl)Cl)C(=O)O
7 4 2 2 white solid 164 2,4-Dichlorobenzoic acid https://pubchem.ncbi.nlm.nih.gov/compound/5787#section=Safety-and-Hazards pubchem.ncbi.nlm.nih.gov en 07 Warning 302 315 319 335 261 264 264+265 270 271 280 301+317 302+352 304+340 305+351+338 319 321 330 332+317 337+317 362+364 403+233 405 501
2,4-Dichlorobenzoic acid is an organic compound with the formula C6H3Cl2CO2H. It is one of more important of several isomers of dichlorobenzoic acid.
It can be prepared by oxidation of 2,4-dichlorotoluene.Takao Maki, Kazuo Takeda "Benzoic Acid and Derivatives" in Ullmann's Encyclopedia of Industrial Chemistry 2002, Wiley-VCH, Weinheim. 10.1002/14356007.a03_555. The coenzyme A thioester of 2,4-dichlorobenzoic acid is the substrate for 2,4-dichlorobenzoyl reductase.
Applications
2,4-Dichlorobenzoic acid has a role to play in the production of the following agents: Lobenzarit,((Denny, W. A.)), ((Atwell, G. J.)), ((Baguley, B. C.)) Journal of Medicinal Chemistry Potential antitumor agents. Part 38. 3-Substituted 5-carboxamido derivatives of amsacrine 26 11 1619–1625 November 1983 https://pubs.acs.org/doi/abs/10.1021/jm00365a013 10.1021/jm00365a013 subscription Furosemide,((Sturm, K.)), ((Siedel, W.)), ((Weyer, R.)), ((Ruschig, H.)) Chemische Berichte Zur Chemie des Furosemids, I. Synthesen von 5‐Sulfamoyl‐anthranilsäure‐Derivaten 99 1 328–344 January 1966 https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cber.19660990150 0009-2940 10.1002/cber.19660990150 28 August 2026 subscription Mepacrine (page 572),((Vardanyan, R. S.)), ((Hruby, V. J.)) 2006 Synthesis of essential drugs Elsevier 9780444521668 M-12325.((Castañer, J.)), ((Hopkins, S. J.)) Drugs of the Future M-12,325 8 3 206 1983 http://journals.prous.com/journals/servlet/xmlxsl/pk_journals.xml_summary_pr?p_JournalId=2&p_RefId=63669&p_IsPs=N 0377-8282 10.1358/dof.1983.008.03.63669 28 August 2026 subscription TO-115 [82050-51-9]
References
Category:Benzoic acids