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(−)-menthol monooxygenase
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Class of enzymes
(−)-menthol monooxygenase 1.14.13.46 117590-75-7 0047505
(−)-menthol monooxygenase (1.14.13.46) is an enzyme that catalyzes the chemical reaction
55% menthol
+ NADPH + H+
O2 H2O
Q27088421 p-menthane-3,8-diol
+ NADP+
The four substrates of this enzyme are (−)-menthol, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen, and a proton. Its products are p-menthane-3,8-diol, oxidised NADP+, and water.1.14.13.46 Madyastha KM, Srivatsan V 1988 Studies on the metabolism of l-menthol in rats Drug Metab. Dispos. 16 765–72 2906604 5 10.1016/S0090-9556(25)07052-7
This enzyme is an oxidoreductase, acting on paired donors, with molecular oxygen as oxidant and incorporating one of its atoms. The systematic name of this enzyme class is (−)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating). This enzyme is also called l-menthol monooxygenase.
Uses
Use of (−)-menthol monooxygenase has been explored by several companies including Procter & Gamble for cleaning products."Cleaning compositions comprising a specific oxygenase"|Alfons, Ivan Maurice et al.|https://patents.google.com/patent/EP1002040B2/en"Methods for conducting assays for enzyme activity on protein microarrays"|Zhou, Fang X.; Schweitzer, Barry| https://patents.google.com/patent/US7635572B2/en?oq=US7635572B2"Cleaning compositions contain a specific oxygenase"|Barnabas, Mary et al.|https://patents.google.com/patent/DE69727704T3/en
References
Biology no
Category:EC 1.14.13
Category:NADPH-dependent enzymes
Category:Enzymes of unknown structure