2-MCPD

2-mcpd.svg 120 2-Chloropropane-1,3-diol 2-monochloropropane-1,3-diol 497-04-1 9913 207-834-6 10337 N6ZZ93MWJ4 1S/C3H7ClO2/c4-3(1-5)2-6/h3,5-6H,1-2H2 DYPJJAAKPQKWTM-UHFFFAOYSA-N C(C(CO)Cl)O 3 7 2 1 colorless liquid 295 18 mmHg 2-MCPD (2-chloropropane-1,3-diol) is an organic chemical compound with the formula ClCH(CH2(OH))2. It is a colorless liquid. The compound has attracted notoreity as a food contaminant. Together with the 3-MCPD, it is one of two chloropropanols food contaminants.10.1021/es903383a 20163179 Identifying New Persistent and Bioaccumulative Organics Among Chemicals in Commerce Environmental Science & Technology 44 7 2277–2285 2010 Howard Philip H. Muir Derek C. G. 2010EnST...44.2277H free It is suspected to be carcinogenic in humans.10.2903/j.efsa.2016.4426 Risks for human health related to the presence of 3- and 2-monochloropropanediol (MCPD), and their fatty acid esters, and glycidyl fatty acid esters in food EFSA Journal 2016 14 5 free 2164/7793 free 2-MCPD, together with its isomer 3-MCPD, is thought to be produced when fat-containing foods are treated at high temperatures with hydrochloric acid. Such treatments are sometimes used to accelerate protein hydrolysis, making food more digestable. In such a treatment chloride is thought to react with the glycerol backbone of lipids to produce 2- and 3-MCPD. Further reading 10.5740/jaoacint.19-0026 2-Monochloropropanediol (2-MCPD), 3-Monochloropropanediol (3-MCPD), and Glycidol in Infant and Adult/Pediatric Nutritional Formula: Single-Laboratory Validation, First Action 2018.12 2019 Kuhlmann Jan Journal of AOAC International 102 4 1205–1220 30992094 25354796 2015 Buhrke T. Frenzel F. Kuhlmann J. Lampen A. 2-Chloro-1,3-propanediol (2-MCPD) and its fatty acid esters: Cytotoxicity, metabolism, and transport by human intestinal Caco-2 cells Archives of Toxicology 89 12 2243–2251 10.1007/s00204-014-1395-3 2015ArTox..89.2243B References 30em External links 3-Chloro-1,2-propandiol Chloropropanols (WHO Food Additive Series 32) Category:Diols Category:IARC Group 2B carcinogens Category:Organochlorides Category:Spermatotoxicants Category:Chlorohydrins