1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase

Class of enzymesJuly 2025 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase 1.3.1.68 0018521 In enzymology, a 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase (1.3.1.68) is an enzyme that catalyzes the chemical reaction 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ 3-methylcatechol + NADH + CO2 Thus, the two substrates of this enzyme are 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate and NAD+, whereas its 3 products are 3-methylcatechol, NADH, and CO2. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating). This enzyme participates in toluene and xylene degradation. References 1 Higson FK, Focht DD 1992 Degradation of 2-methylbenzoic acid by Pseudomonas cepacia MB2 Appl. Environ. Microbiol. 58 194–200 1371658 1 10.1128/aem.58.1.194-200.1992 195191 1992ApEnM..58..194H Biology no Category:EC 1.3.1 Category:NADH-dependent enzymes Category:Enzymes of unknown structure