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2-oxoadipate reductase
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Class of enzymes
2-oxoadipate reductase 1.1.1.172 61116-21-0 0047550
In enzymology, 2-oxoadipate reductase (1.1.1.172) is an enzyme that catalyzes the chemical reaction
50% Q27124358 (R)-2-hydroxyadipic acid
+ NAD+
reversible H+ H+
2-Oxoadipic acid
+ NADH
The two substrates of this enzyme are (R)-2-hydroxyadipic acid and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 2-oxoadipic acid, reduced NADH, and a proton.1.1.1.172Suda T, Robinson JC, Fjellstedt TA 1976 Purification and properties of alpha-ketoadipate reductase, a newly discovered enzyme from human placenta Arch. Biochem. Biophys. 176 610–20 185965 10.1016/0003-9861(76)90205-8 2
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-hydroxyadipate:NAD+ 2-oxidoreductase. Other names in common use include 2-ketoadipate reductase, alpha-ketoadipate reductase, and 2-ketoadipate reductase.
References
Biology no
Category:EC 1.1.1
Category:NADH-dependent enzymes
Category:Enzymes of unknown structure