2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)

Class of enzymes 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) 1.14.11.34 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) (1.14.11.34, ethylene-forming enzyme, EFE) is an enzyme with systematic name L-arginine,2-oxoglutarate:oxygen oxidoreductase (succinate-forming). Nagahama K, Ogawa T, Fujii T, Tazaki M, Tanase S, Morino Y, Fukuda H Purification and properties of an ethylene-forming enzyme from Pseudomonas syringae pv. phaseolicola PK2 Journal of General Microbiology 137 10 2281–6 October 1991 1770346 10.1099/00221287-137-10-2281 free Fukuda H, Ogawa T, Tazaki M, Nagahama K, Fujii T, Tanase S, Morino Y Two reactions are simultaneously catalyzed by a single enzyme: the arginine-dependent simultaneous formation of two products, ethylene and succinate, from 2-oxoglutarate by an enzyme from Pseudomonas syringae Biochemical and Biophysical Research Communications 188 2 483–9 October 1992 1445291 10.1016/0006-291X(92)91081-Z 1992BBRC..188..483F Fukuda H, Ogawa T, Ishihara K, Fujii T, Nagahama K, Omata T, Inoue Y, Tanase S, Morino Y Molecular cloning in Escherichia coli, expression, and nucleotide sequence of the gene for the ethylene-forming enzyme of Pseudomonas syringae pv. phaseolicola PK2 Biochemical and Biophysical Research Communications 188 2 826–32 October 1992 1445325 10.1016/0006-291X(92)91131-9 1992BBRC..188..826F This enzyme catalyses the following chemical reaction 2-oxoglutarate + L-arginine + O2 succinate + CO2 + guanidine + (S)-1-pyrroline-5-carboxylate + H2O (overall reaction) (1a) 2-oxoglutarate + L-arginine + O2 succinate + CO2 + L-hydroxyarginine (1b) L-hydroxyarginine guanidine + (S)-1-pyrroline-5-carboxylate + H2O 2-oxoglutarate/L-arginine monooxygenase/decarboxylase catalyses two cycles of the ethylene-forming reaction. References External links 2-oxoglutarate/L-arginine+monooxygenase/decarboxylase+(succinate-forming) Biology no Category:EC 1.14.11