1-Deoxypentalenic acid 11beta-hydroxylase

Class of enzymes 1-deoxypentalenic acid 11beta-hydroxylase 1.14.11.35 1-deoxypentalenic acid 11beta-hydroxylase (1.14.11.35, PTLH (gene), SAV2991 (gene), PNTH (gene)) is an enzyme with systematic name 1-deoxypentalenic acid,2-oxoglutarate:oxygen oxidoreductase. You Z, Omura S, Ikeda H, Cane DE Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlH, a non-heme iron dioxygenase of Streptomyces avermitilis Journal of the American Chemical Society 128 20 6566–7 May 2006 16704250 2533727 10.1021/ja061469i 2006JAChS.128.6566Y You Z, Omura S, Ikeda H, Cane DE, Jogl G Crystal structure of the non-heme iron dioxygenase PtlH in pentalenolactone biosynthesis The Journal of Biological Chemistry 282 50 36552–60 December 2007 17942405 3010413 10.1074/jbc.M706358200 free This enzyme catalyses the following chemical reaction 1-deoxypentalenate + 2-oxoglutarate + O2 1-deoxy-11beta-hydroxypentalenate + succinate + CO2 1-Deoxypentalenic acid 11beta-hydroxylase contains Fe(II) and ascorbate. References External links 1-deoxypentalenic+acid+11beta-hydroxylase Biology no Category:EC 1.14.11