411 REFERENCE · Wikipedia
2-Quinolone
Reference material by Wikipedia contributors. This retains its source identity and is not 411 news reporting.
December 2021
2-Quinolone.svg 180px Quinolin-2(1H)-one Carbostyril 1,2-Dihydro-2-oxoquinoline 1H-Quinolin-2-one 59-31-4 6038 5816 200-420-6 803BHY7QWU CHEMBL186422 16365 C06338 1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11) LISFMEBWQUVKPJ-UHFFFAOYSA-N C1=CC=C2C(=C1)C=CC(=O)N2 9 7 1 1 solid 199.5
2-Quinolone is an organic compound related structurally to quinoline. It is the majority tautomer in equilibrium with 2-quinolinol. The compound can be classified as a cyclic amide, and as such is used as an isostere for peptides and other pharmaceutically inspired targets.The structural use of carbostyril in physiologically active substances Tashima, Toshihiko Bioorganic & Medicinal Chemistry Letters 2015 25 17 3415–3419 26112444 10.1016/j.bmcl.2015.06.027https://webbook.nist.gov/cgi/cbook.cgi?ID=59-31-4&Units=SI 2(1H)-Quinolinone NIST August 16, 2023 The 4-methyl-2-quinolone can be prepared by dehydration of acetoacetanilide.10.15227/orgsyn.024.0068 free 4-Methylcarbostyril Organic Syntheses 1944 24 68 W. M. Lauer C. E. Kaslow
thumb|left|2-Quinolone (right) and its tautomer 2-hydroxyquinoline (left)
The isomer 4-quinolone is the parent of a large class of antibiotics called quinolone antibiotics. A prominent example is ciprofloxacin, a broad spectrum antibiotic commonly used for treatment of various infections such as urinary tract infections (UTIs), typhoid, meningitis, gonorrhoea, syphilis,2023-06-20 Ciprofloxacin For The Treatment Of STDs: What You Need To Know Allo Health https://www.allohealth.care/healthfeed/stds/ciprofloxacin-for-std 2024-02-08 www.allohealth.care en-GB and skin infections.2022-12-14 About ciprofloxacin https://www.nhs.uk/medicines/ciprofloxacin/about-ciprofloxacin/ 2024-02-08 nhs.uk en
References
External links