2-Phosphoglyceric acid

changed 477215471 2-Phosphoglycerate.png skin-invert 180px 3-Hydroxy-2-(phosphonooxy)propanoic acid 2PG correct chemspider 58 changed EBI 24344 C00631 1/C3H7O7P/c4-1-2(3(5)6)10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9) GXIURPTVHJPJLF-UHFFFAOYAQ O=P(O)(O)OC(C(=O)O)CO correct chemspider 1S/C3H7O7P/c4-1-2(3(5)6)10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9) correct chemspider GXIURPTVHJPJLF-UHFFFAOYSA-N changed ?? 2553-59-5 59 C(C(C(=O)O)OP(=O)(O)O)O 3 7 7 1 2-Phosphoglyceric acid (2PG), or 2-phosphoglycerate, is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate. 2-Phosphoglyceric acid is an intermediate that is part of the glycolysis pathway, and it is converted into phosphoenolpyruvate (PEP) by an enolase.Ji Hong Wang Jianfa Guo Jingru Li Yue Lian Shuai Guo Wenjin Yang Huanmin Kong Fanzhi Zhen Li Guo Li Liu Yanzhi 2016-03-01 Progress in the biological function of alpha-enolase Animal Nutrition 2 1 12–17 10.1016/j.aninu.2016.02.005 29767008 5941012 2405-6545 There are three types of enolase enzymes that are able to catalyze the conversion of 2-phosphoglyceric acid into PEP, which are alpha-enolase, beta-enolase, and gamma-enolase.Didiasova Miroslava Schaefer Liliana Wygrecka Malgorzata 2019-04-26 When Place Matters: Shuttling of Enolase-1 Across Cellular Compartments Frontiers in Cell and Developmental Biology English 7 61 10.3389/fcell.2019.00061 free 31106201 6498095 2296-634X Studies have found that alpha-enolase is the most common enolase, so it is often the specific enolase used to convert 2-phosphoglyceric acid into PEP. Alpha-enolase catalyzes this conversion process by acting as a hydrolase, which means that alpha-enolase removes a water molecule from the 2-phosphoglyceric acid in order to form PEP.Huang Chen Kai Sun Ying Lv Lei Ping Yong 2022-03-17 ENO1 and Cancer Molecular Therapy - Oncolytics English 24 288–298 10.1016/j.omto.2021.12.026 2372-7705 35434271 8987341 In glycolysis 3-phospho-D-glycerate Phosphoglyceromutase 2-phospho-D-glycerate Enolase phosphoenolpyruvate 90px   image:2-phospho-D-glycerate_wpmp.png   image:phosphoenolpyruvate_wpmp.png H2O 75px 75px H2O       Phosphoglyceromutase   Enolase C00197 5.4.2.1 C00631 4.2.1.11 C00074 2-Phosphoglyceric_acid See also 3-Phosphoglyceric acid References Category:Organophosphates Category:Glycolysis