16BO133

Strain of virus Sarbecovirus Betacoronavirus pandemicum 16BO133 16BO133 is a SARS-like coronavirus (SL-COV) which was found in the greater horseshoe bat in South Korea. It was published in 2019 and its genome was completely sequenced. The sequenced Korean SARSr-CoV strain belongs to the severe acute respiratory syndrome coronavirus 1, and its genome sequence similarity is 82.8%. Discovery The 16BO133 virus was discovered in the oral cavity of the greater horseshoe bat in 2016. The genome of this virus strain is 29075 nt. Among SARSr-CoVs, 16BO133 is the closest to the JTMC15 virus, which was published in 2016 and discovered in Jilin, China, with a genome nucleic acid sequence similarity of 98.3%. Compared with other SARSr-CoVs, these two viruses have the ORF8 strain due to a frameshift mutation at the end of ORF7b.Kim Y, Son K, Kim YS, Lee SY, Jheong W, Oem JK Complete genome analysis of a SARS-like bat coronavirus identified in the Republic of Korea. Virus Genes 2019 55 4 545–549 31076983 10.1007/s11262-019-01668-w 7089380 Xu L, Zhang F, Yang W, Jiang T, Lu G, He B, etal Detection and characterization of diverse alpha- and betacoronaviruses from bats in China. Virol Sin 2016 31 1 69–77 26847648 10.1007/s12250-016-3727-3 7090707 The similarity of the genome nucleic acid sequence of 16BO133 virus and SARS-CoV is 82.8%.Na EJ, Lee SY, Kim HJ, Oem JK Comparative genetic analyses of Korean bat coronaviruses with SARS-CoV and the newly emerged SARS-CoV-2. J Vet Sci 2021 22 1 e12 33522164 10.4142/jvs.2021.22.e12 7850784 Although other SARSr-CoV strains have been found in Korea in the past (B15-21 virus, etc.), none of them have been sequenced.Kim HK, Yoon SW, Kim DJ, Koo BS, Noh JY, Kim JH, etal Detection of Severe Acute Respiratory Syndrome-Like, Middle East Respiratory Syndrome-Like Bat Coronaviruses and Group H Rotavirus in Faeces of Korean Bats. Transbound Emerg Dis 2016 63 4 365–72 27213718 10.1111/tbed.12515 7169817 The 16BO133 virus is the first Korean SARSr-CoV strain to be completely sequenced. Phylogenetic See also Bat coronavirus RaTG13 References Q105759613 Category:Bat virome Category:SARS-related coronavirus Category:Infraspecific virus taxa