2-APBT

2-APBT.svg skin-invert-image 225px Serotonin–norepinephrine–dopamine releasing agent None 103861-05-8 22463352 13468670 1-(1-benzothiophen-2-yl)propan-2-amine 11 13 1 1 CC(CC1=CC2=CC=CC=C2S1)N 1S/C11H13NS/c1-8(12)6-10-7-9-4-2-3-5-11(9)13-10/h2-5,7-8H,6,12H2,1H3 LQRQTYOYXPEWJR-UHFFFAOYSA-N 2-APBT is a monoamine releasing agent (MRA) of the benzothiophene family. Brandt SD, Carlino L, Kavanagh PV, Westphal F, Dreiseitel W, Dowling G, Baumann MH, Sitte HH, Halberstadt AL Syntheses and analytical characterizations of novel (2-aminopropyl)benzo[b]thiophene (APBT) based stimulants Drug Test Anal 12 8 1109–1125 August 2020 32372465 8281332 10.1002/dta.2813 Rudin D, McCorvy JD, Glatfelter GC, Luethi D, Szöllősi D, Ljubišić T, Kavanagh PV, Dowling G, Holy M, Jaentsch K, Walther D, Brandt SD, Stockner T, Baumann MH, Halberstadt AL, Sitte HH (2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice Neuropsychopharmacology 47 4 914–923 March 2022 34750565 8882185 10.1038/s41386-021-01221-0 It acts specifically as a fairly well-balanced serotonin–norepinephrine–dopamine releasing agent (SNDRA), with EC50 half-maximal effective concentration values of 8.9nM for serotonin, 21.6nM for norepinephrine, and 38.6nM for dopamine in rat brain synaptosomes. 2-APBT was first described in the scientific literature by 2020. See also Substituted benzothiophene 3-APBT References External links 2-APBT - Isomer Design Category:Amines Category:Benzothiophenes Category:Designer drugs Category:Entactogens